tetano
Editor, Senior Moderator
Pediatr Radiol
. 2020 Oct 21.
doi: 10.1007/s00247-020-04826-7. Online ahead of print.
Overview of chest involvement at computed tomography in children with coronavirus disease 2019 (COVID-19)
Xuehua Peng[SUP] 1 [/SUP], Yu Guo[SUP] 1 [/SUP], Han Xiao[SUP] 2 [/SUP], Wei Xia[SUP] 1 [/SUP], Aiguo Zhai[SUP] 1 [/SUP], Baiqi Zhu[SUP] 1 [/SUP], Wenhan Zhang[SUP] 1 [/SUP], Jianbo Shao[SUP] 3 4 [/SUP]
Affiliations
Abstract
Background: Chest computed tomography (CT) findings in children with coronavirus disease 2019 (COVID-19) have been rarely reported in a comprehensive and systematic manner.
Objective: We investigated the chest CT findings in children with COVID-19, and explored the differences in these findings between symptomatic patients and asymptomatic patients.
Materials and methods: Demographic findings, clinical characteristics, duration of hospital stay and viral shedding, and chest CT findings in 201 children infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) were retrospectively analyzed from January 15 to March 20, 2020, and divided into two groups: symptomatic group (n=136) and asymptomatic group (n=65). Chi-square test and Student's t-test were used for statistical analysis.
Results: Symptomatic patients were mainly young children ≤3 years old (54/63, 86%),while asymptomatic patients were mainly children ≥ 6 years old (51/111, 46%). Fever (41%) and cough (41%) were the most common symptoms. Overall, 119/201 (59%) patients had chest CT findings, and symptomatic patients accounted for 82% (98/119). The CT findings presented as bilateral multiple lesions (60/119, 50.4%), ground-glass opacities (83/119, 70%) and/or consolidation (44/119, 37%) with a peripheral and subpleural distribution (62/83, 75%). Fifteen of 87 (7.2%) patients with lung lesions showed complete lesion absorption, and 42/87 (48%) improved within a mean of 9.1 (standard deviation [SD] 3.2) days. The mean duration of viral shedding was 8.7 (SD 4.9) days. Pleural effusion was very rare. No lymphadenopathy was found in either group.
Conclusion: Symptoms associated with pulmonary involvement were most common in infants and young children. The lung lesions of most patients were absorbed and improved in about 9 days.
Keywords: COVID-19; Chest; Children; Computed tomography; Lungs; SARS-CoV-2.
. 2020 Oct 21.
doi: 10.1007/s00247-020-04826-7. Online ahead of print.
Overview of chest involvement at computed tomography in children with coronavirus disease 2019 (COVID-19)
Xuehua Peng[SUP] 1 [/SUP], Yu Guo[SUP] 1 [/SUP], Han Xiao[SUP] 2 [/SUP], Wei Xia[SUP] 1 [/SUP], Aiguo Zhai[SUP] 1 [/SUP], Baiqi Zhu[SUP] 1 [/SUP], Wenhan Zhang[SUP] 1 [/SUP], Jianbo Shao[SUP] 3 4 [/SUP]
Affiliations
- PMID: 33084963
- DOI: 10.1007/s00247-020-04826-7
Abstract
Background: Chest computed tomography (CT) findings in children with coronavirus disease 2019 (COVID-19) have been rarely reported in a comprehensive and systematic manner.
Objective: We investigated the chest CT findings in children with COVID-19, and explored the differences in these findings between symptomatic patients and asymptomatic patients.
Materials and methods: Demographic findings, clinical characteristics, duration of hospital stay and viral shedding, and chest CT findings in 201 children infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) were retrospectively analyzed from January 15 to March 20, 2020, and divided into two groups: symptomatic group (n=136) and asymptomatic group (n=65). Chi-square test and Student's t-test were used for statistical analysis.
Results: Symptomatic patients were mainly young children ≤3 years old (54/63, 86%),while asymptomatic patients were mainly children ≥ 6 years old (51/111, 46%). Fever (41%) and cough (41%) were the most common symptoms. Overall, 119/201 (59%) patients had chest CT findings, and symptomatic patients accounted for 82% (98/119). The CT findings presented as bilateral multiple lesions (60/119, 50.4%), ground-glass opacities (83/119, 70%) and/or consolidation (44/119, 37%) with a peripheral and subpleural distribution (62/83, 75%). Fifteen of 87 (7.2%) patients with lung lesions showed complete lesion absorption, and 42/87 (48%) improved within a mean of 9.1 (standard deviation [SD] 3.2) days. The mean duration of viral shedding was 8.7 (SD 4.9) days. Pleural effusion was very rare. No lymphadenopathy was found in either group.
Conclusion: Symptoms associated with pulmonary involvement were most common in infants and young children. The lung lesions of most patients were absorbed and improved in about 9 days.
Keywords: COVID-19; Chest; Children; Computed tomography; Lungs; SARS-CoV-2.