tetano
Editor, Senior Moderator
Pediatr Neurol
. 2023 May 19;146:65-78.
doi: 10.1016/j.pediatrneurol.2023.05.011. Online ahead of print. Neurological Manifestations of Coronavirus Disease 2019 and Monkeypox in Pediatric Patients and Their Management: A State-of-the-Art Systematic Review
Novonil Deb[SUP] 1 [/SUP], Poulami Roy[SUP] 2 [/SUP], Anuradha Biswakarma[SUP] 3 [/SUP], Therese Mary[SUP] 4 [/SUP], Sanah Mahajan[SUP] 5 [/SUP], Javeria Khan[SUP] 6 [/SUP], Aatam Shah[SUP] 6 [/SUP]
Affiliations
Background: There is an increasing number of cases being reported of neurological manifestations of Coronavirus disease 2019 (COVID-19) infection and monkeypox, both during the course of the infection and as a presenting symptom. We aim to review the neurological manifestations of COVID-19 and monkeypox in pediatric patients and their management.
Methods: We conducted a systematic review that included cohort studies and case series or reports involving a pediatric population of patients with a confirmed COVID-19 or monkeypox infection and their neurological manifestations. We searched the following electronic databases: PubMed, EMBASE, and Scopus.
Results: From 1136 articles identified, 127 studies were included. Headache, stroke, Guillain-Barré syndrome, seizure, nerve palsies, and multisystem inflammatory syndrome in children were the most common neurological symptoms caused by COVID-19, whereas encephalitis was commonly seen in patients with monkeypox. Rare neurological manifestations of COVID-19 included cerebral venous sinus thrombosis, plexopathies, demyelinating disorders, encephalitis, etc., and rare neurological manifestations of monkeypox included headache.
Conclusions: Our review highlights the importance of investigating possible neurological manifestations and closely monitoring these patients to develop a better understanding of the treatment strategies that can be adopted.
Keywords: COVID-19; Monkeypox; Neurology; Pediatric.
. 2023 May 19;146:65-78.
doi: 10.1016/j.pediatrneurol.2023.05.011. Online ahead of print. Neurological Manifestations of Coronavirus Disease 2019 and Monkeypox in Pediatric Patients and Their Management: A State-of-the-Art Systematic Review
Novonil Deb[SUP] 1 [/SUP], Poulami Roy[SUP] 2 [/SUP], Anuradha Biswakarma[SUP] 3 [/SUP], Therese Mary[SUP] 4 [/SUP], Sanah Mahajan[SUP] 5 [/SUP], Javeria Khan[SUP] 6 [/SUP], Aatam Shah[SUP] 6 [/SUP]
Affiliations
- PMID: 37441883
- DOI: 10.1016/j.pediatrneurol.2023.05.011
Background: There is an increasing number of cases being reported of neurological manifestations of Coronavirus disease 2019 (COVID-19) infection and monkeypox, both during the course of the infection and as a presenting symptom. We aim to review the neurological manifestations of COVID-19 and monkeypox in pediatric patients and their management.
Methods: We conducted a systematic review that included cohort studies and case series or reports involving a pediatric population of patients with a confirmed COVID-19 or monkeypox infection and their neurological manifestations. We searched the following electronic databases: PubMed, EMBASE, and Scopus.
Results: From 1136 articles identified, 127 studies were included. Headache, stroke, Guillain-Barré syndrome, seizure, nerve palsies, and multisystem inflammatory syndrome in children were the most common neurological symptoms caused by COVID-19, whereas encephalitis was commonly seen in patients with monkeypox. Rare neurological manifestations of COVID-19 included cerebral venous sinus thrombosis, plexopathies, demyelinating disorders, encephalitis, etc., and rare neurological manifestations of monkeypox included headache.
Conclusions: Our review highlights the importance of investigating possible neurological manifestations and closely monitoring these patients to develop a better understanding of the treatment strategies that can be adopted.
Keywords: COVID-19; Monkeypox; Neurology; Pediatric.