tetano
Editor, Senior Moderator
Pediatr Infect Dis J
. 2023 Sep 22.
doi: 10.1097/INF.0000000000004093. Online ahead of print. The Clinical Course of SARS-CoV-2 Infection in Patients With Autoimmune Neutropenia: A Retrospective Case Series Study
Gioacchino Andrea Rotulo[SUP] 1 [/SUP], Giulia Ceglie[SUP] 2 3 [/SUP], Annalisa Candino[SUP] 4 [/SUP], Antonella Merola[SUP] 4 [/SUP], Elisa Profeti[SUP] 4 [/SUP], Carmela Giancotta[SUP] 1 [/SUP], Stefania Mercadante[SUP] 4 [/SUP], Veronica Santilli[SUP] 1 [/SUP], Nicola Cotugno[SUP] 1 [/SUP], Paolo Palma[SUP] 1 5 [/SUP], Giuseppe Palumbo[SUP] 2 5 [/SUP], Andrea Finocchi[SUP] 1 5 [/SUP]
Affiliations
Severe acute respiratory syndrome coronavirus 2 infection in children with autoimmune neutropenia may be a cause for concern. In this retrospective study, none of the 24 autoimmune neutropenia cases manifested severe coronavirus disease 2019. We found a significant improvement in neutrophils and a reduction in lymphocytes at post-infection follow-up compared with the median of previous values. We speculate that this paradoxical effect may be due to postinfection immunological phenomena.
. 2023 Sep 22.
doi: 10.1097/INF.0000000000004093. Online ahead of print. The Clinical Course of SARS-CoV-2 Infection in Patients With Autoimmune Neutropenia: A Retrospective Case Series Study
Gioacchino Andrea Rotulo[SUP] 1 [/SUP], Giulia Ceglie[SUP] 2 3 [/SUP], Annalisa Candino[SUP] 4 [/SUP], Antonella Merola[SUP] 4 [/SUP], Elisa Profeti[SUP] 4 [/SUP], Carmela Giancotta[SUP] 1 [/SUP], Stefania Mercadante[SUP] 4 [/SUP], Veronica Santilli[SUP] 1 [/SUP], Nicola Cotugno[SUP] 1 [/SUP], Paolo Palma[SUP] 1 5 [/SUP], Giuseppe Palumbo[SUP] 2 5 [/SUP], Andrea Finocchi[SUP] 1 5 [/SUP]
Affiliations
- PMID: 37773636
- DOI: 10.1097/INF.0000000000004093
Severe acute respiratory syndrome coronavirus 2 infection in children with autoimmune neutropenia may be a cause for concern. In this retrospective study, none of the 24 autoimmune neutropenia cases manifested severe coronavirus disease 2019. We found a significant improvement in neutrophils and a reduction in lymphocytes at post-infection follow-up compared with the median of previous values. We speculate that this paradoxical effect may be due to postinfection immunological phenomena.