tetano
Editor, Senior Moderator
Pediatr Infect Dis J
. 2020 Oct 9.
doi: 10.1097/INF.0000000000002940. Online ahead of print.
Severity of Respiratory Infections With Seasonal Coronavirus Is Associated With Viral and Bacterial Coinfections
Emma M de Koff[SUP] 1 2 [/SUP], Marlies A van Houten[SUP] 1 3 [/SUP], Elisabeth A M Sanders[SUP] 2 4 [/SUP], Debby Bogaert[SUP] 2 5 [/SUP]
Affiliations
Abstract
The clinical presentation of human coronavirus (HCoV) infections in children varies strongly. We show that children with an HCoV-associated lower respiratory tract infection more frequently had respiratory syncytial virus codetected and higher abundance of Haemophilus influenzae/haemolyticus than asymptomatic HCoV carriers as well as children with a non-HCoV-associated lower respiratory tract infection. Viral and bacterial cooccurrence may drive symptomatology of HCoV-associated infections including coronavirus disease 2019.
. 2020 Oct 9.
doi: 10.1097/INF.0000000000002940. Online ahead of print.
Severity of Respiratory Infections With Seasonal Coronavirus Is Associated With Viral and Bacterial Coinfections
Emma M de Koff[SUP] 1 2 [/SUP], Marlies A van Houten[SUP] 1 3 [/SUP], Elisabeth A M Sanders[SUP] 2 4 [/SUP], Debby Bogaert[SUP] 2 5 [/SUP]
Affiliations
- PMID: 33044434
- DOI: 10.1097/INF.0000000000002940
Abstract
The clinical presentation of human coronavirus (HCoV) infections in children varies strongly. We show that children with an HCoV-associated lower respiratory tract infection more frequently had respiratory syncytial virus codetected and higher abundance of Haemophilus influenzae/haemolyticus than asymptomatic HCoV carriers as well as children with a non-HCoV-associated lower respiratory tract infection. Viral and bacterial cooccurrence may drive symptomatology of HCoV-associated infections including coronavirus disease 2019.