tetano
Editor, Senior Moderator
Pediatr Infect Dis J
. 2021 Jun 22.
doi: 10.1097/INF.0000000000003244. Online ahead of print.
Ischemic Lesions in the Brain of a Neonate With SARS-CoV2 Infection
Andrea C Brum[SUP] 1 [/SUP], M Patricia Glasman[SUP] 1 [/SUP], M Cristina De Luca[SUP] 1 [/SUP], Carlos A Rugilo[SUP] 1 2 [/SUP], M Ines Urquizu Handal[SUP] 1 [/SUP], Armando O Picon[SUP] 1 [/SUP], Cristina Cook[SUP] 1 3 [/SUP], Nestor E Vain[SUP] 1 4 [/SUP]
Affiliations
Abstract
Aim: To describe a term newborn with acquired severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and multisystem involvement including seizures associated to ischemic lesions in the brain.
Background: Coronavirus disease 2019 (COVID-19) is predominantly a respiratory infection, but it may affect many other systems. Most pediatric COVID-19 cases range from asymptomatic to mild-moderate disease. There are no specific clinical signs described for neonatal COVID-19 infections. In children, severe central nervous system compromise has been rarely reported.
Case description: We describe a 17-day-old newborn who acquired a SARS-CoV-2 infection in a family meeting that was admitted for fever, seizures and lethargy and in whom consumption coagulopathy, ischemic lesions in the brain and cardiac involvement were documented.
Conclusions: SARS-CoV-2 neonatal infection can be associated with multi-organic involvement. In our patient, significant central nervous system compromise associated to ischemic lesions and laboratory findings of consumption coagulopathy were found.
Clinical significance: Although neonatal SARS-CoV-2 infections are infrequent, they can be associated with multi-organic involvement. Neonatologists and pediatricians should be aware of this unusual way of presentation of COVID-19 in newborn infants.
. 2021 Jun 22.
doi: 10.1097/INF.0000000000003244. Online ahead of print.
Ischemic Lesions in the Brain of a Neonate With SARS-CoV2 Infection
Andrea C Brum[SUP] 1 [/SUP], M Patricia Glasman[SUP] 1 [/SUP], M Cristina De Luca[SUP] 1 [/SUP], Carlos A Rugilo[SUP] 1 2 [/SUP], M Ines Urquizu Handal[SUP] 1 [/SUP], Armando O Picon[SUP] 1 [/SUP], Cristina Cook[SUP] 1 3 [/SUP], Nestor E Vain[SUP] 1 4 [/SUP]
Affiliations
- PMID: 34288632
- DOI: 10.1097/INF.0000000000003244
Abstract
Aim: To describe a term newborn with acquired severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and multisystem involvement including seizures associated to ischemic lesions in the brain.
Background: Coronavirus disease 2019 (COVID-19) is predominantly a respiratory infection, but it may affect many other systems. Most pediatric COVID-19 cases range from asymptomatic to mild-moderate disease. There are no specific clinical signs described for neonatal COVID-19 infections. In children, severe central nervous system compromise has been rarely reported.
Case description: We describe a 17-day-old newborn who acquired a SARS-CoV-2 infection in a family meeting that was admitted for fever, seizures and lethargy and in whom consumption coagulopathy, ischemic lesions in the brain and cardiac involvement were documented.
Conclusions: SARS-CoV-2 neonatal infection can be associated with multi-organic involvement. In our patient, significant central nervous system compromise associated to ischemic lesions and laboratory findings of consumption coagulopathy were found.
Clinical significance: Although neonatal SARS-CoV-2 infections are infrequent, they can be associated with multi-organic involvement. Neonatologists and pediatricians should be aware of this unusual way of presentation of COVID-19 in newborn infants.