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Pediatr Infect Dis J . Decreasing Incidence of the Multisystem Inflammatory Syndrome in Children Over 3 Pandemic Waves

tetano

Editor, Senior Moderator
Pediatr Infect Dis J


. 2023 Feb 1;42(2):122-124.
doi: 10.1097/INF.0000000000003766. Epub 2022 Nov 7.
Decreasing Incidence of the Multisystem Inflammatory Syndrome in Children Over 3 Pandemic Waves


Irini Eleftheriou[SUP] 1 [/SUP], Despina Maritsi[SUP] 1 [/SUP], Stavroula Lampidi[SUP] 1 [/SUP], Konstantina Charisi[SUP] 2 [/SUP], Petrina Vantsi[SUP] 2 [/SUP], Kleopatra Skourti[SUP] 3 [/SUP], Filippos Filippatos[SUP] 3 [/SUP], Ioannis Amplianitis[SUP] 4 [/SUP], Despina Dimou[SUP] 5 [/SUP], Kyriaki Papadopoulou-Legbelou[SUP] 6 [/SUP], Efimia Papadopoulou-Alataki[SUP] 6 [/SUP], Parthena Kampouridou[SUP] 7 [/SUP], Patra Koletsi[SUP] 5 [/SUP], Lampros Fotis[SUP] 8 [/SUP], Elena Vergadi[SUP] 9 [/SUP], Despoina Gkentzi[SUP] 4 [/SUP], Evangelia Farmaki[SUP] 10 [/SUP], Vassiliki Papaevangelou[SUP] 8 [/SUP], Emmanouil Galanakis[SUP] 9 [/SUP], Ioanna N Grivea[SUP] 11 [/SUP], George A Syrogiannopoulos[SUP] 11 [/SUP], Vana Spoulou[SUP] 3 [/SUP], Nikos Spyridis[SUP] 1 [/SUP], Athanasios Michos[SUP] 3 [/SUP], Emmanuel Roilides[SUP] 2 [/SUP], Maria N Tsolia[SUP] 1 [/SUP]



Affiliations

Abstract

In this nationwide retrospective study, a substantial decline in the incidence of multisystem inflammatory syndrome in children over 3 successive pandemic waves characterized by different severe acute respiratory syndrome coronavirus 2 variants was documented-from 3.4 of 1000 to 1.1 of 1000 and finally to 0.25 of 1000 confirmed severe acute respiratory syndrome coronavirus 2 positive cases (P < 0.0001), respectively, whereas clinical findings and severity did not significantly vary.
 
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