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Pediatr Infect Dis J . Comorbidities Associated With Different Degrees of Severity in Children and Young People Hospitalized With Acute COVID-19

tetano

Editor, Senior Moderator
Pediatr Infect Dis J


. 2025 Jan 9.
doi: 10.1097/INF.0000000000004684. Online ahead of print. Comorbidities Associated With Different Degrees of Severity in Children and Young People Hospitalized With Acute COVID-19

Irati Gastesi[SUP] 1 [/SUP], Sara Domínguez-Rodríguez[SUP] 1 2 [/SUP], Marthe Le Prevost[SUP] 3 [/SUP], Andrea Ramírez[SUP] 4 [/SUP], Carlo Giaquinto[SUP] 5 6 [/SUP], María Lucía Mesa[SUP] 7 [/SUP], Alvaro Ballesteros[SUP] 1 [/SUP], Charlotte Jackson[SUP] 3 [/SUP], Pablo Vásquez-Hoyos[SUP] 8 [/SUP], Carlos Alvarez Moreno[SUP] 9 [/SUP], Carlos Grasa[SUP] 10 11 [/SUP], Cristina Epalza[SUP] 12 [/SUP], Antoni Soriano-Arandes[SUP] 13 [/SUP], Cinta Moraleda[SUP] 1 12 [/SUP], Alfredo Tagarro[SUP] 1 2 14 [/SUP]



Affiliations
Abstract

In this prospective cohort study with 2326 hospitalized children and young people with coronavirus disease 2019 in Spain and Colombia, 36.4% had comorbidities. Asthma, recurrent wheezing, chronic neurological, cardiac and pulmonary diseases significantly increased the risk of severe outcomes such as death, mechanical ventilation and intensive care unit admission. The incremental risk with additional comorbidities underscores the importance of targeted vaccination strategies for vulnerable children and young people populations.


 
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