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Pediatr Blood Cancer . Effects of COVID-19 vaccination on platelet counts and bleeding in children, adolescents, and young adults with immune thromb

tetano

tetano

Editor, Senior Moderator
Pediatr Blood Cancer


. 2022 Nov 1;e30051.
doi: 10.1002/pbc.30051. Online ahead of print.
Effects of COVID-19 vaccination on platelet counts and bleeding in children, adolescents, and young adults with immune thrombocytopenia


Shipra Kaicker[SUP] 1 [/SUP], Kirsten Martinko[SUP] 1 [/SUP], James B Bussel[SUP] 1 [/SUP]



Affiliations

Abstract

Coronavirus disease 2019 (COVID-19) vaccines rarely cause de novo immune thrombocytopenia (ITP) but may worsen preexisting ITP in adults. Whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines impact platelet counts and bleeding in children, adolescents, and young adults (C-AYA) with preexisting ITP is unknown. We report here the very limited effect of COVID-19 vaccination on platelet counts and bleeding in a single-center series of 2 C-AYA with ITP. No patient experienced worsening bleeding and only one child had a significant decrease in platelet count which improved spontaneously to her baseline without intervention. SARS-CoV2 vaccination was safe in C-AYA with ITP in this small cohort.

Keywords: COVID-19; SARS-CoV-2 vaccine; children; immune thrombocytopenia (ITP).
 
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