tetano
Editor, Senior Moderator
Pediatr Blood Cancer
. 2022 Mar 6;e29647.
doi: 10.1002/pbc.29647. Online ahead of print.
Coronavirus disease 2019 and vaccination in patients with Shwachman-Diamond syndrome
Thomas J Galletta[SUP] 1 [/SUP], Sara K Loveless[SUP] 2 [/SUP], Maggie M Malsch[SUP] 3 [/SUP], Akiko Shimamura[SUP] 4 5 [/SUP], Kasiani C Myers[SUP] 2 6 [/SUP]
Affiliations
Abstract
Because they can experience neutropenia due to bone marrow failure, patients with Shwachman-Diamond syndrome (SDS) carry increased risk for serious infections compared with the general population; however, there has been a paucity of data on the incidence and severity of coronavirus disease 2019 (COVID-19) in patients with SDS. We compiled results from a survey distributed to participants in the SDS Registry in May-June 2021. In this report, we describe the characteristics and outcomes of patients with SDS who had COVID-19. Patients reported a short clinical course without significant complications or cytopenias. Additionally, COVID-19 vaccines were well tolerated with minor side effects.
Keywords: Bone marrow failure; COVID-19; general hematology; infections in immunocompromised hosts; infectious disease; vaccines; viral infection.
. 2022 Mar 6;e29647.
doi: 10.1002/pbc.29647. Online ahead of print.
Coronavirus disease 2019 and vaccination in patients with Shwachman-Diamond syndrome
Thomas J Galletta[SUP] 1 [/SUP], Sara K Loveless[SUP] 2 [/SUP], Maggie M Malsch[SUP] 3 [/SUP], Akiko Shimamura[SUP] 4 5 [/SUP], Kasiani C Myers[SUP] 2 6 [/SUP]
Affiliations
- PMID: 35253346
- DOI: 10.1002/pbc.29647
Abstract
Because they can experience neutropenia due to bone marrow failure, patients with Shwachman-Diamond syndrome (SDS) carry increased risk for serious infections compared with the general population; however, there has been a paucity of data on the incidence and severity of coronavirus disease 2019 (COVID-19) in patients with SDS. We compiled results from a survey distributed to participants in the SDS Registry in May-June 2021. In this report, we describe the characteristics and outcomes of patients with SDS who had COVID-19. Patients reported a short clinical course without significant complications or cytopenias. Additionally, COVID-19 vaccines were well tolerated with minor side effects.
Keywords: Bone marrow failure; COVID-19; general hematology; infections in immunocompromised hosts; infectious disease; vaccines; viral infection.