tetano
Editor, Senior Moderator
Pathogens
. 2022 Feb 8;11(2):221.
doi: 10.3390/pathogens11020221.
Evaluation of Betacoronavirus OC43 and SARS-CoV-2 Elimination by Zefero Air Sanitizer Device in a Novel Laboratory Recirculation System
Marco Sebastiano Nicolò[SUP] 1 [/SUP], Maria Giovanna Rizzo[SUP] 1 [/SUP], Nicoletta Palermo[SUP] 1 [/SUP], Concetta Gugliandolo[SUP] 1 [/SUP], Salvatore Cuzzocrea[SUP] 1 [/SUP], Salvatore P P Guglielmino[SUP] 1 [/SUP]
Affiliations
Abstract
Indoor air sanitizers contrast airborne diseases and particularly severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/Coronavirus disease 2019 (COVID-19). The commercial air sanitizer Zefero (Cf7 S.r.l., San Giovanni La Punta, Italy) works alternatively using a set of integrated disinfecting technologies (namely Photocatalysis/UV mode) or by generating ozone (Ozone mode). Here we evaluated the virucidal efficacy of Zefero setup modes against human Betacoronavirus OC43 and SARS-CoV-2. For this purpose, we designed a laboratory test system in which each virus, as aerosol, was treated with Photocatalysis/UV or Ozone mode and returned into a recirculation plexiglass chamber. Aerosol samples were collected after different times of exposure, corresponding to different volumes of air treated. The viral RNA concentration was determined by qRT-PCR. In Photocatalysis/UV mode, viral RNA of OC43 or SARS-CoV-2 was not detected after 120 or 90 min treatment, respectively, whereas in Ozone mode, viruses were eliminated after 30 or 45 min, respectively. Our results indicated that the integrated technologies used in the air sanitizer Zefero are effective in eliminating both viruses. As a reliable experimental system, the recirculation chamber developed in this study represents a suitable apparatus for effectively comparing the disinfection capacity of different air sanitizers.
Keywords: OC43; SARS-CoV-2; air sanitization; airborne disease viruses; virus decontamination.
. 2022 Feb 8;11(2):221.
doi: 10.3390/pathogens11020221.
Evaluation of Betacoronavirus OC43 and SARS-CoV-2 Elimination by Zefero Air Sanitizer Device in a Novel Laboratory Recirculation System
Marco Sebastiano Nicolò[SUP] 1 [/SUP], Maria Giovanna Rizzo[SUP] 1 [/SUP], Nicoletta Palermo[SUP] 1 [/SUP], Concetta Gugliandolo[SUP] 1 [/SUP], Salvatore Cuzzocrea[SUP] 1 [/SUP], Salvatore P P Guglielmino[SUP] 1 [/SUP]
Affiliations
- PMID: 35215162
- DOI: 10.3390/pathogens11020221
Abstract
Indoor air sanitizers contrast airborne diseases and particularly severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/Coronavirus disease 2019 (COVID-19). The commercial air sanitizer Zefero (Cf7 S.r.l., San Giovanni La Punta, Italy) works alternatively using a set of integrated disinfecting technologies (namely Photocatalysis/UV mode) or by generating ozone (Ozone mode). Here we evaluated the virucidal efficacy of Zefero setup modes against human Betacoronavirus OC43 and SARS-CoV-2. For this purpose, we designed a laboratory test system in which each virus, as aerosol, was treated with Photocatalysis/UV or Ozone mode and returned into a recirculation plexiglass chamber. Aerosol samples were collected after different times of exposure, corresponding to different volumes of air treated. The viral RNA concentration was determined by qRT-PCR. In Photocatalysis/UV mode, viral RNA of OC43 or SARS-CoV-2 was not detected after 120 or 90 min treatment, respectively, whereas in Ozone mode, viruses were eliminated after 30 or 45 min, respectively. Our results indicated that the integrated technologies used in the air sanitizer Zefero are effective in eliminating both viruses. As a reliable experimental system, the recirculation chamber developed in this study represents a suitable apparatus for effectively comparing the disinfection capacity of different air sanitizers.
Keywords: OC43; SARS-CoV-2; air sanitization; airborne disease viruses; virus decontamination.