tetano
Editor, Senior Moderator
Pathogens
. 2023 Dec 29;13(1):35.
doi: 10.3390/pathogens13010035. Comparative Pathology of Animal Models for Influenza A Virus Infection
Natalie M Kirk[SUP] 1 [/SUP], Yuying Liang[SUP] 1 [/SUP], Hinh Ly[SUP] 1 [/SUP]
Affiliations
Animal models are essential for studying disease pathogenesis and to test the efficacy and safety of new vaccines and therapeutics. For most diseases, there is no single model that can recapitulate all features of the human condition, so it is vital to understand the advantages and disadvantages of each. The purpose of this review is to describe popular comparative animal models, including mice, ferrets, hamsters, and non-human primates (NHPs), that are being used to study clinical and pathological changes caused by influenza A virus infection with the aim to aid in appropriate model selection for disease modeling.
Keywords: IAV; IBV; animal models; influenza virus; pathogenesis; pathology; respiratory pathogens.
. 2023 Dec 29;13(1):35.
doi: 10.3390/pathogens13010035. Comparative Pathology of Animal Models for Influenza A Virus Infection
Natalie M Kirk[SUP] 1 [/SUP], Yuying Liang[SUP] 1 [/SUP], Hinh Ly[SUP] 1 [/SUP]
Affiliations
- PMID: 38251342
- DOI: 10.3390/pathogens13010035
Animal models are essential for studying disease pathogenesis and to test the efficacy and safety of new vaccines and therapeutics. For most diseases, there is no single model that can recapitulate all features of the human condition, so it is vital to understand the advantages and disadvantages of each. The purpose of this review is to describe popular comparative animal models, including mice, ferrets, hamsters, and non-human primates (NHPs), that are being used to study clinical and pathological changes caused by influenza A virus infection with the aim to aid in appropriate model selection for disease modeling.
Keywords: IAV; IBV; animal models; influenza virus; pathogenesis; pathology; respiratory pathogens.