tetano
Editor, Senior Moderator
Clinical Infectious Diseases 2010;51:000?000
? 2010 by the Infectious Diseases Society of America. All rights reserved.
1058-4838/2010/5111-00XX$15.00
DOI: 10.1086/657121
BRIEF REPORT
Pandemic Influenza A (H1N1) Outbreak among 15 School‐Aged HIV‐1?Infected Children
Cornelia Feiterna‐Sperling,1
Anke Edelmann,2
Renate Nickel,1
Klaus Magdorf,1
Frank Bergmann,3
Peter Rautenberg,5
Brunhilde Schweiger,4
Volker Wahn,1
Detlev H. Kr?ger,2 and
J?rg Hofmann2
1Department of Pediatric Pneumology and Immunology, 2Institute of Medical Virology, Helmut‐Ruska‐Haus, and 3Department of Internal Medicine, Division of Infectious Diseases and Pulmonary Medicine, Charit? Universit?tsmedizin Berlin, 4National Reference Center for Influenza, Robert Koch Institute, Berlin, and 5Institute for Infection Medicine, Universit?tsklinikum Schleswig‐Holstein, Kiel, Germany
Patients infected with human immunodeficiency virus type 1 (HIV‐1) are considered to be at increased risk for 2009 H1N1 influenza?related complications. We performed an observational study after an outbreak of 2009 H1N1 influenza virus infection among a group of 15 HIV‐1?infected school‐aged children in Germany in October 2009. Clinical course, kinetics of viral shedding, and antibody response among children with CD4 cell counts >350 cells/μL and 2009 H1N1 influenza virus coinfection did not appear to differ from that among healthy children. Oseltamivir shortened the duration of viral shedding.
http://www.journals.uchicago.edu/doi/abs/10.1086/657121
? 2010 by the Infectious Diseases Society of America. All rights reserved.
1058-4838/2010/5111-00XX$15.00
DOI: 10.1086/657121
BRIEF REPORT
Pandemic Influenza A (H1N1) Outbreak among 15 School‐Aged HIV‐1?Infected Children
Cornelia Feiterna‐Sperling,1
Anke Edelmann,2
Renate Nickel,1
Klaus Magdorf,1
Frank Bergmann,3
Peter Rautenberg,5
Brunhilde Schweiger,4
Volker Wahn,1
Detlev H. Kr?ger,2 and
J?rg Hofmann2
1Department of Pediatric Pneumology and Immunology, 2Institute of Medical Virology, Helmut‐Ruska‐Haus, and 3Department of Internal Medicine, Division of Infectious Diseases and Pulmonary Medicine, Charit? Universit?tsmedizin Berlin, 4National Reference Center for Influenza, Robert Koch Institute, Berlin, and 5Institute for Infection Medicine, Universit?tsklinikum Schleswig‐Holstein, Kiel, Germany
Patients infected with human immunodeficiency virus type 1 (HIV‐1) are considered to be at increased risk for 2009 H1N1 influenza?related complications. We performed an observational study after an outbreak of 2009 H1N1 influenza virus infection among a group of 15 HIV‐1?infected school‐aged children in Germany in October 2009. Clinical course, kinetics of viral shedding, and antibody response among children with CD4 cell counts >350 cells/μL and 2009 H1N1 influenza virus coinfection did not appear to differ from that among healthy children. Oseltamivir shortened the duration of viral shedding.
http://www.journals.uchicago.edu/doi/abs/10.1086/657121