tetano
Editor, Senior Moderator
Zoonoses Public Health. 2017 Jun 23. doi: 10.1111/zph.12370. [Epub ahead of print]
[h=1]Pandemic (H1N1) 2009 influenza A virus infection associated with respiratory signs in sloth bears (Melursus ursinus).[/h] Boedeker NC[SUP]1[/SUP], Nelson MI[SUP]2[/SUP], Killian ML[SUP]3[/SUP], Torchetti MK[SUP]3[/SUP], Barthel T[SUP]1[/SUP], Murray S[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] In 2009, a pandemic influenza A virus (pH1N1) spread globally in humans and infected a broad range of captive animals with close human contact. In February 2014, a pH1N1 virus was isolated from a sloth bear with respiratory signs at a US zoo, demonstrating that recurring epidemics present an ongoing threat to animals, including threatened species. This is the first report of pH1N1 infection in sloth bears. To understand the sloth bear virus within the global context of pH1N1, phylogenetic trees were inferred including full-length sequences from available non-human, non-swine hosts, representing four families in the order Carnivora and one order of birds. A combination of phylogenetic and epidemiological evidence strongly suggests the sloth bear was infected with a human-origin pH1N1 virus, supporting the implementation of biosecurity measures to protect human and animal health.
? 2017 Blackwell Verlag GmbH.
[h=4]KEYWORDS:[/h] Melursus ursinus ; genomics; influenza A virus; pH1N1; reverse zoonosis; sloth bear
PMID: 28646559 DOI: 10.1111/zph.12370
[h=1]Pandemic (H1N1) 2009 influenza A virus infection associated with respiratory signs in sloth bears (Melursus ursinus).[/h] Boedeker NC[SUP]1[/SUP], Nelson MI[SUP]2[/SUP], Killian ML[SUP]3[/SUP], Torchetti MK[SUP]3[/SUP], Barthel T[SUP]1[/SUP], Murray S[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] In 2009, a pandemic influenza A virus (pH1N1) spread globally in humans and infected a broad range of captive animals with close human contact. In February 2014, a pH1N1 virus was isolated from a sloth bear with respiratory signs at a US zoo, demonstrating that recurring epidemics present an ongoing threat to animals, including threatened species. This is the first report of pH1N1 infection in sloth bears. To understand the sloth bear virus within the global context of pH1N1, phylogenetic trees were inferred including full-length sequences from available non-human, non-swine hosts, representing four families in the order Carnivora and one order of birds. A combination of phylogenetic and epidemiological evidence strongly suggests the sloth bear was infected with a human-origin pH1N1 virus, supporting the implementation of biosecurity measures to protect human and animal health.
? 2017 Blackwell Verlag GmbH.
[h=4]KEYWORDS:[/h] Melursus ursinus ; genomics; influenza A virus; pH1N1; reverse zoonosis; sloth bear
PMID: 28646559 DOI: 10.1111/zph.12370