tetano
Editor, Senior Moderator
Osong Public Health Res Perspect
. 2021 Feb;12(1):37-43.
doi: 10.24171/j.phrp.2021.12.1.06.
Genomic Surveillance of SARS-CoV-2: Distribution of Clades in the Republic of Korea in 2020
Ae Kyung Park[SUP] 1 [/SUP], Il-Hwan Kim[SUP] 1 [/SUP], Junyoung Kim[SUP] 2 [/SUP], Jeong-Min Kim[SUP] 1 [/SUP], Heui Man Kim[SUP] 1 [/SUP], Chae Young Lee[SUP] 1 [/SUP], Myung-Guk Han[SUP] 3 [/SUP], Gi-Eun Rhie[SUP] 4 [/SUP], Donghyok Kwon[SUP] 5 [/SUP], Jeong-Gu Nam[SUP] 6 [/SUP], Young-Joon Park[SUP] 7 [/SUP], Jin Gwack[SUP] 7 [/SUP], Nam-Joo Lee[SUP] 1 [/SUP], SangHee Woo[SUP] 1 [/SUP], Jin Sun No[SUP] 4 [/SUP], Jaehee Lee[SUP] 1 [/SUP], Jeemin Ha[SUP] 8 [/SUP], JeeEun Rhee[SUP] 1 [/SUP], Cheon-Kwon Yoo[SUP] 9 [/SUP], Eun-Jin Kim[SUP] 1 [/SUP]
Affiliations
Abstract
Since a novel beta-coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in December 2019, there has been a rapid global spread of the virus. Genomic surveillance was conducted on samples isolated from infected individuals to monitor the spread of genetic variants of SARS-CoV-2 in Korea. The Korea Disease Control and Prevention Agency performed whole genome sequencing of SARS-CoV-2 in Korea for 1 year (January 2020 to January 2021). A total of 2,488 SARS-CoV-2 cases were sequenced (including 648 cases from abroad). Initially, the prevalent clades of SARS-CoV-2 were the S and V clades, however, by March 2020, GH clade was the most dominant. Only international travelers were identified as having G or GR clades, and since the first variant 501Y.V1 was identified (from a traveler from the United Kingdom on December 22[SUP]nd[/SUP], 2020), a total of 27 variants of 501Y.V1, 501Y.V2, and 484K.V2 have been classified (as of January 25[SUP]th[/SUP], 2021). The results in this study indicated that quarantining of travelers entering Korea successfully prevented dissemination of the SARS-CoV-2 variants in Korea.
Keywords: Republic of Korea; SARS-CoV-2; whole-genome sequencing.
. 2021 Feb;12(1):37-43.
doi: 10.24171/j.phrp.2021.12.1.06.
Genomic Surveillance of SARS-CoV-2: Distribution of Clades in the Republic of Korea in 2020
Ae Kyung Park[SUP] 1 [/SUP], Il-Hwan Kim[SUP] 1 [/SUP], Junyoung Kim[SUP] 2 [/SUP], Jeong-Min Kim[SUP] 1 [/SUP], Heui Man Kim[SUP] 1 [/SUP], Chae Young Lee[SUP] 1 [/SUP], Myung-Guk Han[SUP] 3 [/SUP], Gi-Eun Rhie[SUP] 4 [/SUP], Donghyok Kwon[SUP] 5 [/SUP], Jeong-Gu Nam[SUP] 6 [/SUP], Young-Joon Park[SUP] 7 [/SUP], Jin Gwack[SUP] 7 [/SUP], Nam-Joo Lee[SUP] 1 [/SUP], SangHee Woo[SUP] 1 [/SUP], Jin Sun No[SUP] 4 [/SUP], Jaehee Lee[SUP] 1 [/SUP], Jeemin Ha[SUP] 8 [/SUP], JeeEun Rhee[SUP] 1 [/SUP], Cheon-Kwon Yoo[SUP] 9 [/SUP], Eun-Jin Kim[SUP] 1 [/SUP]
Affiliations
- PMID: 33659153
- PMCID: PMC7899228
- DOI: 10.24171/j.phrp.2021.12.1.06
Abstract
Since a novel beta-coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in December 2019, there has been a rapid global spread of the virus. Genomic surveillance was conducted on samples isolated from infected individuals to monitor the spread of genetic variants of SARS-CoV-2 in Korea. The Korea Disease Control and Prevention Agency performed whole genome sequencing of SARS-CoV-2 in Korea for 1 year (January 2020 to January 2021). A total of 2,488 SARS-CoV-2 cases were sequenced (including 648 cases from abroad). Initially, the prevalent clades of SARS-CoV-2 were the S and V clades, however, by March 2020, GH clade was the most dominant. Only international travelers were identified as having G or GR clades, and since the first variant 501Y.V1 was identified (from a traveler from the United Kingdom on December 22[SUP]nd[/SUP], 2020), a total of 27 variants of 501Y.V1, 501Y.V2, and 484K.V2 have been classified (as of January 25[SUP]th[/SUP], 2021). The results in this study indicated that quarantining of travelers entering Korea successfully prevented dissemination of the SARS-CoV-2 variants in Korea.
Keywords: Republic of Korea; SARS-CoV-2; whole-genome sequencing.