tetano
Editor, Senior Moderator
Clin Pharmacol Ther. 2015 Jun 25. doi: 10.1002/cpt.179. [Epub ahead of print]
[h=1]Oseltamivir for the Treatment of H1N1 Influenza During Pregnancy.[/h] Beigi RH[SUP]1,[/SUP][SUP]2[/SUP], Pillai VC[SUP]3[/SUP], Venkataramanan R[SUP]2,[/SUP][SUP]3,[/SUP][SUP]4[/SUP], Caritis SN[SUP]1,[/SUP][SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Pregnancy heightens the risk of adverse outcomes from influenza infections. This is true for both seasonal epidemics as well as occasional pandemics. Seasonal influenza vaccines are the focus of disease prevention and are recommended for all pregnant women in any trimester of pregnancy and postpartum. Oseltamivir (Tamiflu?) is currently the recommended and most commonly used pharmaceutical agent for influenza prophylaxis and treatment. Oseltamivir has been demonstrated to prevent disease after exposure, treat infected individuals as well as lessen the likelihood of complications. The physiologic adaptations of pregnancy alter the pharmacokinetics of this important drug. Evidence of these alterations, knowledge gaps, and future investigative directions to fill these knowledge gaps are highlighted. This article is protected by copyright. All rights reserved.
? 2015 American Society for Clinical Pharmacology and Therapeutics.
PMID: 26108913 [PubMed - as supplied by publisher]
[h=1]Oseltamivir for the Treatment of H1N1 Influenza During Pregnancy.[/h] Beigi RH[SUP]1,[/SUP][SUP]2[/SUP], Pillai VC[SUP]3[/SUP], Venkataramanan R[SUP]2,[/SUP][SUP]3,[/SUP][SUP]4[/SUP], Caritis SN[SUP]1,[/SUP][SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Pregnancy heightens the risk of adverse outcomes from influenza infections. This is true for both seasonal epidemics as well as occasional pandemics. Seasonal influenza vaccines are the focus of disease prevention and are recommended for all pregnant women in any trimester of pregnancy and postpartum. Oseltamivir (Tamiflu?) is currently the recommended and most commonly used pharmaceutical agent for influenza prophylaxis and treatment. Oseltamivir has been demonstrated to prevent disease after exposure, treat infected individuals as well as lessen the likelihood of complications. The physiologic adaptations of pregnancy alter the pharmacokinetics of this important drug. Evidence of these alterations, knowledge gaps, and future investigative directions to fill these knowledge gaps are highlighted. This article is protected by copyright. All rights reserved.
? 2015 American Society for Clinical Pharmacology and Therapeutics.
PMID: 26108913 [PubMed - as supplied by publisher]