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Organizing pneumonia secondary to influenza infection: Two case reports and a literature review

tetano

Editor, Senior Moderator
Enferm Infecc Microbiol Clin. 2019 May 21. pii: S0213-005X(19)30166-1. doi: 10.1016/j.eimc.2019.04.006. [Epub ahead of print]
[h=1]Organizing pneumonia secondary to influenza infection: Two case reports and a literature review.[/h] [Article in English, Spanish]
Nu?ez-Conde A[SUP]1[/SUP], Marquez-Algaba E[SUP]2[/SUP], Falc? V[SUP]2[/SUP], Almirante B[SUP]2[/SUP], Burgos J[SUP]3[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Organizing pneumonia (OP) is a rare complication of influenza virus infection but scarce data are available. The recognition of this entity is important because require appropriate treatment.
[h=4]METHODS:[/h] We report two cases and perform a systematic review on PubMed database. Only cases with histological confirmation of OP and influenza virus positive laboratory test were included.
[h=4]RESULTS:[/h] We collected 16 patients. Median age was 52 year, 20% of patients were smokers and 43.8% had not any comorbidity. Influenza A virus infection was diagnosed in 75%. Clinical manifestation consisted on a respiratory deterioration with a median time of appearance of 14 days. Radiological pattern observed was ground-glass opacities with consolidations. Survival was observed in 12 patients (75%). All three patients who did not receive steroid treatment died.
[h=4]CONCLUSION:[/h] Physicians must be aware that patients with influenza infection with a torpid course could be developing OP and prompt corticoid therapy should be instaured.
Copyright ? 2019 Elsevier Espa?a, S.L.U. and Sociedad Espa?ola de Enfermedades Infecciosas y Microbiolog?a Cl?nica. All rights reserved.


[h=4]KEYWORDS:[/h] Bronchiolitis obliterans organizing pneumonia; Bronquiolitis obliterante; Cryptogenic organizing pneumonia; Influenza virus; Neumon?a organizativa citogen?tica; Neumon?a organizativa secundaria; Secondary organizing pneumonia; Virus de la gripe

PMID: 31126691 DOI: 10.1016/j.eimc.2019.04.006
 
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