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Open Forum Infect Dis . Severe Acute Respiratory Syndrome Coronavirus 2 Lethality Did not Change Over Time in Two Italian Provinces

tetano

Editor, Senior Moderator
Open Forum Infect Dis


. 2020 Nov 12;7(12):ofaa556.
doi: 10.1093/ofid/ofaa556. eCollection 2020 Dec.
Severe Acute Respiratory Syndrome Coronavirus 2 Lethality Did not Change Over Time in Two Italian Provinces


Maria Elena Flacco[SUP] 1 [/SUP], Cecilia Acuti Martellucci[SUP] 2 [/SUP], Francesca Bravi[SUP] 3 [/SUP], Giustino Parruti[SUP] 4 [/SUP], Alfonso Mascitelli[SUP] 5 [/SUP], Lorenzo Mantovani[SUP] 6 7 [/SUP], Stefania Boccia[SUP] 8 9 [/SUP], Lamberto Manzoli[SUP] 1 [/SUP]



Affiliations

Abstract

This retrospective cohort study included all the subjects diagnosed with severe acute respiratory syndrome coronavirus 2 infection (n = 2493) in 2 Italian provinces. Two hundred fifty-eight persons died, after a median of 14.0 ? 11.0 days. Adjusting for age, gender, and main comorbidities, the ≥28-day case-fatality rate did not decrease from March to April 2020 (adjusted hazard ratio, 0.93; P = .6).

Keywords: COVID-19; SARS-CoV-2; case-fatality rate; lethality; trend over time.
 
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