Open Forum Infect Dis . SARS-CoV-2 Viral Load on Admission Is Associated With 30-Day Mortality

[tetano]

Open Forum Infect Dis


. 2020 Nov 3;7(12)faa535.
doi: 10.1093/ofid/ofaa535. eCollection 2020 Dec.
SARS-CoV-2 Viral Load on Admission Is Associated With 30-Day Mortality


Andrew Bryan[SUP] 1 [/SUP], Susan L Fink[SUP] 1 [/SUP], Meghan A Gattuso[SUP] 2 [/SUP], Gregory Pepper[SUP] 1 [/SUP], Anu Chaudhary[SUP] 1 [/SUP], Mark H Wener[SUP] 1 3 [/SUP], Chihiro Morishima[SUP] 1 [/SUP], Keith R Jerome[SUP] 1 4 [/SUP], Patrick C Mathias[SUP] 1 5 [/SUP], Alexander L Greninger[SUP] 1 4 [/SUP]



Affiliations

• PMID: 33349793
• PMCID: PMC7665729
• DOI: 10.1093/ofid/ofaa535

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load on admission was associated with a significantly increased 30-day mortality (odds ratio [OR], 4.20; 95% CI, 1.62-10.86), and anti-SARS-CoV-2 nucleocapisid IgG seropositivity on admission trended toward a reduced 30-day mortality (OR, 0.43; 95% CI, 0.15-1.26). Reporting of quantitative SARS-CoV-2 viral load and serologic assays may offer prognostic clinical information.

Keywords: SARS-CoV-2; quantitative; serology; viral load.