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Open Forum Infect Dis . Prevalence of SARS-CoV-2 Viremia in Presymptomatic Blood Donors in the Delta and Omicron Variant Eras

tetano

Editor, Senior Moderator
Open Forum Infect Dis


. 2023 May 9;10(5):ofad253.
doi: 10.1093/ofid/ofad253. eCollection 2023 May. Prevalence of SARS-CoV-2 Viremia in Presymptomatic Blood Donors in the Delta and Omicron Variant Eras

Paula Saá[SUP] 1 [/SUP], Rebecca V Fink[SUP] 2 [/SUP], Hina Dawar[SUP] 3 [/SUP], Clara Di Germanio[SUP] 3 4 [/SUP], Leilani Montalvo[SUP] 3 [/SUP], David J Wright[SUP] 2 [/SUP], David E Krysztof[SUP] 1 [/SUP], Steven H Kleinman[SUP] 5 [/SUP], Theresa Nester[SUP] 6 [/SUP], Debra A Kessler[SUP] 7 [/SUP], Rebecca L Townsend[SUP] 1 [/SUP], Bryan R Spencer[SUP] 1 [/SUP], Hany Kamel[SUP] 8 [/SUP], Jackie Vannoy[SUP] 8 [/SUP], Michael P Busch[SUP] 3 4 [/SUP], Susan L Stramer[SUP] 1 [/SUP], Mars Stone[SUP] 3 4 [/SUP], Philip J Norris[SUP] 3 4 9 [/SUP]; NHLBI Recipient Epidemiology and Donor Evaluation Study-IV-Pediatric (REDS-IV-P)



Affiliations
Abstract

Presymptomatic plasma samples from 1596 donors reporting coronavirus disease 2019 infection or symptoms after blood donation were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA and anti-S and anti-N antibodies. Prior infection and vaccination both protected from developing SARS-CoV-2 RNAemia and from symptomatic infection. RNAemia rates did not differ in the Delta and Omicron variant eras.

Keywords: COVID-19; vaccination; viremia.

 
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