tetano
Editor, Senior Moderator
Open Forum Infect Dis
. 2022 Apr 28;9(7)
fac216.
doi: 10.1093/ofid/ofac216. eCollection 2022 Jul.
Medicinal Immunoglobulin G Products (2020) Show High Infectivity Neutralizing Activity Against Seasonal Influenza Virus Strains Selected for Future Vaccines (2020-2022)
José María Díez[SUP] 1 [/SUP], Daniel Casals[SUP] 1 [/SUP], Carolina Romero[SUP] 1 [/SUP], Rodrigo Gajardo[SUP] 1 [/SUP]
Affiliations
Abstract
Immunoglobulin (Ig)G medicinal products manufactured in 2020 were tested for infectivity neutralization and hemagglutination inhibition against World Health Organization-selected influenza strains included in worldwide vaccines 2020-2022. The IgG batches (from US plasma) showed potent activity. Intravenous immunoglobulin could potentially add to therapies for serious influenza cases in immunocompromised patients. Further study is warranted.
Keywords: IgG medicinal products; antibody neutralization; hemagglutination; influenza; vaccination.
. 2022 Apr 28;9(7)
fac216.doi: 10.1093/ofid/ofac216. eCollection 2022 Jul.
Medicinal Immunoglobulin G Products (2020) Show High Infectivity Neutralizing Activity Against Seasonal Influenza Virus Strains Selected for Future Vaccines (2020-2022)
José María Díez[SUP] 1 [/SUP], Daniel Casals[SUP] 1 [/SUP], Carolina Romero[SUP] 1 [/SUP], Rodrigo Gajardo[SUP] 1 [/SUP]
Affiliations
- PMID: 35794931
- PMCID: PMC9253882
- DOI: 10.1093/ofid/ofac216
Abstract
Immunoglobulin (Ig)G medicinal products manufactured in 2020 were tested for infectivity neutralization and hemagglutination inhibition against World Health Organization-selected influenza strains included in worldwide vaccines 2020-2022. The IgG batches (from US plasma) showed potent activity. Intravenous immunoglobulin could potentially add to therapies for serious influenza cases in immunocompromised patients. Further study is warranted.
Keywords: IgG medicinal products; antibody neutralization; hemagglutination; influenza; vaccination.