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Open Forum Infect Dis . Impact of Previous Coronavirus Disease 2019 on Immune Response After a Single Dose of BNT162b2 Severe Acute Respiratory Syn

tetano

tetano

Editor, Senior Moderator
Open Forum Infect Dis


. 2021 Jun 4;8(7):ofab299.
doi: 10.1093/ofid/ofab299. eCollection 2021 Jul.
Impact of Previous Coronavirus Disease 2019 on Immune Response After a Single Dose of BNT162b2 Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine


María Velasco[SUP] 1 [/SUP], Maria Isabel Galán[SUP] 2 [/SUP], Maria Luisa Casas[SUP] 3 [/SUP], Elia Pérez-Fernández[SUP] 4 [/SUP], Diana Martínez-Ponce[SUP] 2 [/SUP], Beatriz González-Piñeiro[SUP] 5 [/SUP], Virgilio Castilla[SUP] 6 [/SUP], Carlos Guijarro[SUP] 7 [/SUP], Alcorcón COVID-19 Working Group



Collaborators, Affiliations

Abstract

Immune response after a single dose of BNT162b2 vaccine was markedly increased in subjects with previous severe acute respiratory syndrome coronavirus 2 infection, reaching similar immunoglobulin titers to those elicited by the full 2 doses in naive cases, and increased modestly after the second dose. These data may inform the priority of the boosting dose.

Keywords: COVID-19; SARS-CoV-2; health care workers; immune response; vaccine.
 
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