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Open Forum Infect Dis . Health Care Workers' Sick Leave due to COVID-19 Vaccination in Context With SARS-CoV-2 Infection and Quarantine-A Multicente

tetano

Editor, Senior Moderator
Open Forum Infect Dis


. 2022 Apr 14;9(7):ofac203.
doi: 10.1093/ofid/ofac203. eCollection 2022 Jul.
Health Care Workers' Sick Leave due to COVID-19 Vaccination in Context With SARS-CoV-2 Infection and Quarantine-A Multicenter Cross-Sectional Survey


Stilla Bauernfeind[SUP] 1 [/SUP], Gunnar Huppertz[SUP] 2 [/SUP], Karolina Mueller[SUP] 2 [/SUP], Florian Hitzenbichler[SUP] 1 [/SUP], Loredana Hardmann[SUP] 1 [/SUP], Sylvia Pemmerl[SUP] 3 [/SUP], Harald Hollnberger[SUP] 4 [/SUP], Wolfgang Sieber[SUP] 5 [/SUP], Matthias Wettstein[SUP] 6 [/SUP], Stephan Seeliger[SUP] 7 [/SUP], Klaus Kienle[SUP] 8 [/SUP], Christian Paetzel[SUP] 9 [/SUP], Norbert Kutz[SUP] 10 [/SUP], Dionys Daller[SUP] 11 [/SUP], Niels Zorger[SUP] 12 [/SUP], Arno Mohr[SUP] 13 [/SUP], Benedikt M J Lampl[SUP] 14 [/SUP], Bernd Salzberger[SUP] 1 [/SUP]



Affiliations
Free PMC article

Abstract

Background: Reactogenicity of coronavirus disease 2019 (COVID-19) vaccines can result in inability to work. The object of this study was to evaluate health care workers' sick leave after COVID-19 vaccination and to compare it with sick leave due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and quarantine leave.
Methods: A multicenter cross-sectional survey was conducted at Regensburg University Medical Center and 10 teaching hospitals in South-East Germany from July 28 to October 15, 2021.
Results: Of 2662 participants, 2309 (91.8%) were fully vaccinated without a history of SARS-CoV-2 infection. Sick leave after first/second vaccination occurred in 239 (10.4%) and 539 (23.3%) participants. In multivariable logistic regression, the adjusted odds ratio for sick leave after first/second vaccination compared with BNT162b2 was 2.26/3.72 for mRNA-1237 (95% CI, 1.28-4.01/1.99-6.96) and 27.82/0.48 for ChAdOx1-S (95% CI, 19.12-40.48/0.24-0.96). The actual median sick leave (interquartile range [IQR]) was 1 (0-2) day after any vaccination. Two hundred fifty-one participants (9.4%) reported a history of SARS-CoV-2 infection (median sick leave [IQR] 14 [10-21] days), 353 (13.3%) were quarantined at least once (median quarantine leave [IQR], 14 [10-14] days). Sick leave due to SARS-CoV-2 infection (4642 days) and quarantine leave (4710 days) accounted for 7.7 times more loss of workforce than actual sick leave after first and second vaccination (1216 days) in all fully vaccinated participants.
Conclusions: Sick leave after COVID-19 vaccination is frequent and is associated with the vaccine applied. COVID-19 vaccination should reduce the much higher proportion of loss of workforce due to SARS-CoV-2 infection and quarantine.

Keywords: COVID-19; SARS-CoV-2 infection; quarantine; sick leave; vaccine reactogenicity.
 
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