tetano
Editor, Senior Moderator
Open Forum Infect Dis
. 2021 Oct 6;8(12)
fab507.
doi: 10.1093/ofid/ofab507. eCollection 2021 Dec.
Graded Administration of Second Dose of Moderna and Pfizer-BioNTech COVID-19 mRNA Vaccines in Patients With Hypersensitivity to First Dose
Linh-An C Tuong[SUP] 1 [/SUP], Peter Capucilli[SUP] 1 [/SUP], Mary Staicu[SUP] 2 [/SUP], Allison Ramsey[SUP] 1 3 [/SUP], Edward E Walsh[SUP] 4 [/SUP], S Shahzad Mustafa[SUP] 1 3 [/SUP]
Affiliations
Abstract
Two mRNA coronavirus disease 2019 (COVID-19) vaccines, Moderna and Pfizer-BioNTech, require 2 doses for maximum efficacy. This case series reports the safety and immunogenicity of a graded administration of the second dose of the Moderna and Pfizer-BioNTech COVID-19 vaccines in patients with immediate hypersensitivity reactions to the first dose.
Keywords: 19; 2 spike protein; COVID; CoV; SARS; graded administration; mRNA vaccine.
. 2021 Oct 6;8(12)
fab507.doi: 10.1093/ofid/ofab507. eCollection 2021 Dec.
Graded Administration of Second Dose of Moderna and Pfizer-BioNTech COVID-19 mRNA Vaccines in Patients With Hypersensitivity to First Dose
Linh-An C Tuong[SUP] 1 [/SUP], Peter Capucilli[SUP] 1 [/SUP], Mary Staicu[SUP] 2 [/SUP], Allison Ramsey[SUP] 1 3 [/SUP], Edward E Walsh[SUP] 4 [/SUP], S Shahzad Mustafa[SUP] 1 3 [/SUP]
Affiliations
- PMID: 34873577
- PMCID: PMC8500168
- DOI: 10.1093/ofid/ofab507
Abstract
Two mRNA coronavirus disease 2019 (COVID-19) vaccines, Moderna and Pfizer-BioNTech, require 2 doses for maximum efficacy. This case series reports the safety and immunogenicity of a graded administration of the second dose of the Moderna and Pfizer-BioNTech COVID-19 vaccines in patients with immediate hypersensitivity reactions to the first dose.
Keywords: 19; 2 spike protein; COVID; CoV; SARS; graded administration; mRNA vaccine.