tetano
Editor, Senior Moderator
Open Forum Infect Dis
. 2024 Aug 28;11(9)
fae481.
doi: 10.1093/ofid/ofae481. eCollection 2024 Sep. Effectiveness of the Original Monovalent and Bivalent COVID-19 Vaccines Against COVID-19-Associated Emergency Department and Urgent Care Encounters in Pregnant Persons Who Were Not Immunocompromised: VISION Network, June 2022-August 2023
Allison Avrich Ciesla[SUP] 1 2 [/SUP], Victoria Lazariu[SUP] 3 [/SUP], Kristin Dascomb[SUP] 4 [/SUP], Stephanie A Irving[SUP] 5 [/SUP], Brian E Dixon[SUP] 6 7 [/SUP], Manjusha Gaglani[SUP] 8 9 10 [/SUP], Allison L Naleway[SUP] 5 [/SUP], Shaun J Grannis[SUP] 6 11 [/SUP], Sarah Ball[SUP] 3 [/SUP], Anupam B Kharbanda[SUP] 12 [/SUP], Gabriela Vazquez-Benitez[SUP] 13 [/SUP], Nicola P Klein[SUP] 14 [/SUP], Karthik Natarajan[SUP] 15 16 [/SUP], Toan C Ong[SUP] 17 [/SUP], Peter J Embi[SUP] 18 [/SUP], Katherine E Fleming-Dutra[SUP] 1 [/SUP], Ruth Link-Gelles[SUP] 1 19 [/SUP], Ousseny Zerbo[SUP] 14 [/SUP]
Affiliations
Pregnant people face increased risk of severe COVID-19. Current guidelines recommend updated COVID-19 vaccination (2023-2024) for those aged ≥6 months, irrespective of pregnancy status. To refine recommendations for pregnant people, further data are needed. Using a test-negative design, we evaluated COVID-19 vaccine effectiveness against medically attended COVID-19 with COVID-19-like illness among pregnant people aged 18 to 45 years during June 2022 to August 2023. When doses were received during pregnancy, vaccine effectiveness was 52% (95% CI, 29%-67%); when received <6 months prior to pregnancy, 28% (95% CI, 11%-42%); and when received ≥6 months prior to pregnancy, 6% (95% CI, -11% to 21%). Pregnant people should stay up-to-date with recommended COVID-19 vaccination.
Keywords: COVID-19; SARS-CoV-2; pregnant persons; public health; vaccine effectiveness.
. 2024 Aug 28;11(9)
fae481.doi: 10.1093/ofid/ofae481. eCollection 2024 Sep. Effectiveness of the Original Monovalent and Bivalent COVID-19 Vaccines Against COVID-19-Associated Emergency Department and Urgent Care Encounters in Pregnant Persons Who Were Not Immunocompromised: VISION Network, June 2022-August 2023
Allison Avrich Ciesla[SUP] 1 2 [/SUP], Victoria Lazariu[SUP] 3 [/SUP], Kristin Dascomb[SUP] 4 [/SUP], Stephanie A Irving[SUP] 5 [/SUP], Brian E Dixon[SUP] 6 7 [/SUP], Manjusha Gaglani[SUP] 8 9 10 [/SUP], Allison L Naleway[SUP] 5 [/SUP], Shaun J Grannis[SUP] 6 11 [/SUP], Sarah Ball[SUP] 3 [/SUP], Anupam B Kharbanda[SUP] 12 [/SUP], Gabriela Vazquez-Benitez[SUP] 13 [/SUP], Nicola P Klein[SUP] 14 [/SUP], Karthik Natarajan[SUP] 15 16 [/SUP], Toan C Ong[SUP] 17 [/SUP], Peter J Embi[SUP] 18 [/SUP], Katherine E Fleming-Dutra[SUP] 1 [/SUP], Ruth Link-Gelles[SUP] 1 19 [/SUP], Ousseny Zerbo[SUP] 14 [/SUP]
Affiliations
- PMID: 39286032
- PMCID: PMC11403472
- DOI: 10.1093/ofid/ofae481
Pregnant people face increased risk of severe COVID-19. Current guidelines recommend updated COVID-19 vaccination (2023-2024) for those aged ≥6 months, irrespective of pregnancy status. To refine recommendations for pregnant people, further data are needed. Using a test-negative design, we evaluated COVID-19 vaccine effectiveness against medically attended COVID-19 with COVID-19-like illness among pregnant people aged 18 to 45 years during June 2022 to August 2023. When doses were received during pregnancy, vaccine effectiveness was 52% (95% CI, 29%-67%); when received <6 months prior to pregnancy, 28% (95% CI, 11%-42%); and when received ≥6 months prior to pregnancy, 6% (95% CI, -11% to 21%). Pregnant people should stay up-to-date with recommended COVID-19 vaccination.
Keywords: COVID-19; SARS-CoV-2; pregnant persons; public health; vaccine effectiveness.