Open Forum Infect Dis . Effectiveness of A Fourth Dose of COVID-19 mRNA Vaccine in the Elderly Population During the Omicron BA.2 and BA.5 Circulat

[tetano]

Open Forum Infect Dis


. 2023 Mar 1;10(3)fad109.
doi: 10.1093/ofid/ofad109. eCollection 2023 Mar.
Effectiveness of A Fourth Dose of COVID-19 mRNA Vaccine in the Elderly Population During the Omicron BA.2 and BA.5 Circulation: A Nationwide Cohort Study in Korea (K-COVE)


Seon Kyeong Park[SUP] 1 [/SUP], Young June Choe[SUP] 2 [/SUP], Eun Jung Jang[SUP] 1 [/SUP], Ryu Kyung Kim[SUP] 1 [/SUP], Do-Sang Lim[SUP] 1 [/SUP], Seonju Yi[SUP] 1 [/SUP], Sangwon Lee[SUP] 1 [/SUP], Geun-Yong Kwon[SUP] 1 [/SUP], Jee Yeon Shin[SUP] 1 [/SUP], Sang-Yoon Choi[SUP] 1 [/SUP], Mi Jin Jeong[SUP] 1 [/SUP], Young-Joon Park[SUP] 1 [/SUP]



Affiliations

• PMID: 36968954
• PMCID: PMC10034752
• DOI: 10.1093/ofid/ofad109

Abstract

We estimate the effectiveness of a fourth dose booster of coronavirus disease 2019 mRNA vaccine in individuals aged ≥60 years during Omicron BA.2 and BA.5 circulation in Korea. The effectiveness against critical infection was 67.7% (95% confidence interval, 50.7%-78.8%) at 31-60 days and 62.1% (95% confidence interval, 45.5%-73.7%) at 61-90 days.

Keywords: COVID-19; SARS-CoV-2; coronavirus; elderly.