tetano
Editor, Senior Moderator
Open Forum Infect Dis
. 2021 Jun 12;8(7)
fab315.
doi: 10.1093/ofid/ofab315. eCollection 2021 Jul.
Effect of Monoclonal Antibody Treatment on Clinical Outcomes in Ambulatory Patients With Coronavirus Disease 2019
Blake Anderson[SUP] 1 [/SUP], Zirka Smith[SUP] 2 [/SUP], Srilatha Edupuganti[SUP] 2 [/SUP], Xiaobo Yan[SUP] 3 [/SUP], Christopher M Masi[SUP] 1 [/SUP], Henry M Wu[SUP] 2 [/SUP]
Affiliations
Abstract
We compared rates of emergency department visits or hospitalizations among ambulatory coronavirus disease 2019 (COVID-19) patients treated with monoclonal antibody (mAb) therapy (n = 305) vs untreated patients (n = 6354). Treatment was associated with decreased encounters within 30 days (adjusted odds ratio, 0.23 [95% confidence interval, .15-.36]). Our findings support treatment of acute COVID-19 with mAbs.
Keywords: COVID-19; SARS-CoV-2; monoclonal antibodies; therapeutics.
. 2021 Jun 12;8(7)
fab315.doi: 10.1093/ofid/ofab315. eCollection 2021 Jul.
Effect of Monoclonal Antibody Treatment on Clinical Outcomes in Ambulatory Patients With Coronavirus Disease 2019
Blake Anderson[SUP] 1 [/SUP], Zirka Smith[SUP] 2 [/SUP], Srilatha Edupuganti[SUP] 2 [/SUP], Xiaobo Yan[SUP] 3 [/SUP], Christopher M Masi[SUP] 1 [/SUP], Henry M Wu[SUP] 2 [/SUP]
Affiliations
- PMID: 34277887
- PMCID: PMC8279096
- DOI: 10.1093/ofid/ofab315
Abstract
We compared rates of emergency department visits or hospitalizations among ambulatory coronavirus disease 2019 (COVID-19) patients treated with monoclonal antibody (mAb) therapy (n = 305) vs untreated patients (n = 6354). Treatment was associated with decreased encounters within 30 days (adjusted odds ratio, 0.23 [95% confidence interval, .15-.36]). Our findings support treatment of acute COVID-19 with mAbs.
Keywords: COVID-19; SARS-CoV-2; monoclonal antibodies; therapeutics.