Open Forum Infect Dis . Demographic and Clinical Factors Associated With Death Among Persons <21 Years Old With Multisystem Inflammatory Syndrome i

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Open Forum Infect Dis


. 2021 Jul 19;8(8)fab388.
doi: 10.1093/ofid/ofab388. eCollection 2021 Aug.
Demographic and Clinical Factors Associated With Death Among Persons <21 Years Old With Multisystem Inflammatory Syndrome in Children-United States, February 2020-March 2021


Anna Bowen[SUP] 1 [/SUP], Allison D Miller[SUP] 1 [/SUP], Laura D Zambrano[SUP] 1 [/SUP], Michael J Wu[SUP] 1 [/SUP], Matthew E Oster[SUP] 1 [/SUP], Shana Godfred-Cato[SUP] 1 [/SUP], Ermias D Belay[SUP] 1 [/SUP], Angela P Campbell[SUP] 1 [/SUP]



Affiliations

• PMID: 34409123
• PMCID: PMC8364981
• DOI: 10.1093/ofid/ofab388

Abstract

Multisystem inflammatory syndrome in children (MIS-C) occurs among persons aged <21 years following severe acute respiratory syndrome coronavirus 2 infection. Among 2818 MIS-C cases, 35 (1.2%) deaths were reported, primarily affecting racial/ethnic minority persons. Being 16-20 years old or having comorbidities was associated with death. Targeting coronavirus disease 2019 prevention among these groups and their caregivers might prevent MIS-C-related deaths.

Keywords: COVID-19; child; death; epidemiology; multisystem inflammatory syndrome in children.