tetano
Editor, Senior Moderator
Open Forum Infect Dis
. 2020 Oct 14;7(11)
faa486.
doi: 10.1093/ofid/ofaa486. eCollection 2020 Nov.
Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study
Say Tat Ooi[SUP] 1 2 [/SUP], Purnima Parthasarathy[SUP] 1 [/SUP], Yi Lin[SUP] 2 [/SUP], Valliammai D/O Nallakaruppan[SUP] 3 [/SUP], Shereen Ng[SUP] 3 [/SUP], Teck Choon Tan[SUP] 4 [/SUP], Serena Low[SUP] 5 [/SUP], Terence Tang[SUP] 6 [/SUP]
Affiliations
Abstract
This is a retrospective cohort study of hospitalized adults with coronavirus disease 2019 (COVID-19). Fifty-seven patients received treatment alone, and 35 patients received treatment with adjunctive prednisolone. A combination of corticosteroids and antivirals was associated with lower risk of clinical progression and invasive mechanical ventilation or death in early COVID-19 pneumonia.
Keywords: COVID-19; corticosteroids; hydroxychloroquine.
. 2020 Oct 14;7(11)
faa486.doi: 10.1093/ofid/ofaa486. eCollection 2020 Nov.
Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study
Say Tat Ooi[SUP] 1 2 [/SUP], Purnima Parthasarathy[SUP] 1 [/SUP], Yi Lin[SUP] 2 [/SUP], Valliammai D/O Nallakaruppan[SUP] 3 [/SUP], Shereen Ng[SUP] 3 [/SUP], Teck Choon Tan[SUP] 4 [/SUP], Serena Low[SUP] 5 [/SUP], Terence Tang[SUP] 6 [/SUP]
Affiliations
- PMID: 33235888
- PMCID: PMC7665708
- DOI: 10.1093/ofid/ofaa486
Abstract
This is a retrospective cohort study of hospitalized adults with coronavirus disease 2019 (COVID-19). Fifty-seven patients received treatment alone, and 35 patients received treatment with adjunctive prednisolone. A combination of corticosteroids and antivirals was associated with lower risk of clinical progression and invasive mechanical ventilation or death in early COVID-19 pneumonia.
Keywords: COVID-19; corticosteroids; hydroxychloroquine.