tetano
Editor, Senior Moderator
One Health
. 2025 Sep 16:21:101211.
doi: 10.1016/j.onehlt.2025.101211. eCollection 2025 Dec. Outbreak of highly pathogenic avian influenza a(H5N1) among house cats: A case series involving oseltamivir treatment
Jacob F Gomez[SUP] 1 [/SUP], Ian G Bemis[SUP] 2 3 [/SUP], Ismaila Shittu[SUP] 4 [/SUP], Gregory C Gray[SUP] 4 5 6 [/SUP], Kristen K Coleman[SUP] 2 3 [/SUP]
Affiliations
We present a highly pathogenic avian influenza A(H5N1) outbreak among four domestic cats from the same household within close proximity to a dairy farm in Tulare, California - the epicenter of the H5N1 dairy cattle outbreaks in California, USA. We demonstrate that with early supportive care and treatment with oseltamivir, H5N1 is survivable in domestic cats, and that survivor cats may maintain high titers of neutralizing antibodies against H5N1 at least 3-4 months post recovery.
Keywords: Avian influenza virus; Cats; Cross-species transmission; Felines; One health; Zoonosis.
. 2025 Sep 16:21:101211.
doi: 10.1016/j.onehlt.2025.101211. eCollection 2025 Dec. Outbreak of highly pathogenic avian influenza a(H5N1) among house cats: A case series involving oseltamivir treatment
Jacob F Gomez[SUP] 1 [/SUP], Ian G Bemis[SUP] 2 3 [/SUP], Ismaila Shittu[SUP] 4 [/SUP], Gregory C Gray[SUP] 4 5 6 [/SUP], Kristen K Coleman[SUP] 2 3 [/SUP]
Affiliations
- PMID: 41031138
- PMCID: PMC12478091
- DOI: 10.1016/j.onehlt.2025.101211
We present a highly pathogenic avian influenza A(H5N1) outbreak among four domestic cats from the same household within close proximity to a dairy farm in Tulare, California - the epicenter of the H5N1 dairy cattle outbreaks in California, USA. We demonstrate that with early supportive care and treatment with oseltamivir, H5N1 is survivable in domestic cats, and that survivor cats may maintain high titers of neutralizing antibodies against H5N1 at least 3-4 months post recovery.
Keywords: Avian influenza virus; Cats; Cross-species transmission; Felines; One health; Zoonosis.