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Ocul Immunol Inflamm . Multiple Evanescent White Dot Syndrome Following Adenovirus Vector-Based COVID-19 Vaccine (Covishield)

tetano

Editor, Senior Moderator
Ocul Immunol Inflamm


. 2023 Apr 12;1-6.
doi: 10.1080/09273948.2023.2192271. Online ahead of print.
Multiple Evanescent White Dot Syndrome Following Adenovirus Vector-Based COVID-19 Vaccine (Covishield)


Abhilasha Baharani[SUP] 1 [/SUP], Raja Rami Reddy[SUP] 2 [/SUP]



Affiliations

Abstract

Purpose: To report a case of multiple evanescent white dot syndrome (MEWDS) following adenovirus vector-based Coronavirus disease 2019 (COVID-19) vaccine, Covishield and to present a summary of previously reported cases of MEWDS following COVID-19 vaccines.
Methods: Retrospective case report and review of literature.
Results: A 22-year-old Indian female presented with blurred vision, scotomata, and photopsias in her left eye, a day after administration of second dose of Covishield vaccine. Her clinical findings and imaging features confirmed the diagnosis of MEWDS. Her symptoms resolved spontaneously after 2 weeks.
Conclusion: This is the first reported case of MEWDS following an adenovirus vector-based COVID-19 vaccine. Comparison with previously reported cases of MEWDS following COVID-19 vaccination showed that patients are generally healthy, young to middle-aged women, who develop symptoms after a median time of one week and recover spontaneously over a median period of 4 weeks.

Keywords: COVID-19; MEWDS; Oxford-AstraZeneca; multiple evanescent white dot syndrome; vaccine associated uveitis.
 
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