tetano
Editor, Senior Moderator
Obesity (Silver Spring)
. 2020 Aug 4.
doi: 10.1002/oby.22937. Online ahead of print.
BMI is Associated with Coronavirus Disease 2019 Intensive Care Unit Admission in African Americans
Ala L Alkhatib[SUP] 1 [/SUP], Jonah Kreniske[SUP] 2 [/SUP], Jerry S Zifodya[SUP] 1 [/SUP], Vivian Fonseca[SUP] 3 [/SUP], Mohammad Tahboub[SUP] 1 [/SUP], Joanna Khatib[SUP] 3 [/SUP], Joshua L Denson[SUP] 1 [/SUP], Joseph A Lasky[SUP] 1 [/SUP], John J Lefante[SUP] 4 [/SUP], Christine M Bojanowski[SUP] 1 [/SUP]
Affiliations
Abstract
Objective: Coronavirus disease 2019 (COVID-19) has disproportionately impacted the African American community. This study aims to identify the risk factors for severe COVID-19 disease in African American patients.
Methods: This was a retrospective cross-sectional analysis of African American patients with COVID-19 treated between March 12 and April 9, 2020, at a single tertiary center. The primary outcome of interest was severe disease defined as those requiring intensive care unit (ICU) admission.
Results: The study included 158 consecutive patients. The mean age was 57 years, and 61% were women. The mean (SD) of BMI was 33.2 (8.6) kg/m[SUP]2[/SUP] . Overall, patients admitted to the ICU were older (62 vs. 55 years, P = 0.003) and had higher BMI (36.5 kg/m[SUP]2[/SUP] vs. 31.9 kg/m[SUP]2[/SUP] , P = 0.002). In unadjusted and adjusted analysis, the factors most associated with ICU admission in this sample were age (adjusted odds ratio [aOR]: 1.073; 95% CI: 1.033-1.114), BMI (aOR: 1.115; 95% CI: 1.052-1.182), and lung disease (aOR: 3.097; 95% CI: 1.137-8.437).
Conclusions: This study identified risk factors for severe disease in COVID-19, specifically in an African American population. Further inclusive research aimed at optimizing clinical care relevant to the African American population is critical to ensure an equitable response to COVID-19.
. 2020 Aug 4.
doi: 10.1002/oby.22937. Online ahead of print.
BMI is Associated with Coronavirus Disease 2019 Intensive Care Unit Admission in African Americans
Ala L Alkhatib[SUP] 1 [/SUP], Jonah Kreniske[SUP] 2 [/SUP], Jerry S Zifodya[SUP] 1 [/SUP], Vivian Fonseca[SUP] 3 [/SUP], Mohammad Tahboub[SUP] 1 [/SUP], Joanna Khatib[SUP] 3 [/SUP], Joshua L Denson[SUP] 1 [/SUP], Joseph A Lasky[SUP] 1 [/SUP], John J Lefante[SUP] 4 [/SUP], Christine M Bojanowski[SUP] 1 [/SUP]
Affiliations
- PMID: 32748568
- DOI: 10.1002/oby.22937
Abstract
Objective: Coronavirus disease 2019 (COVID-19) has disproportionately impacted the African American community. This study aims to identify the risk factors for severe COVID-19 disease in African American patients.
Methods: This was a retrospective cross-sectional analysis of African American patients with COVID-19 treated between March 12 and April 9, 2020, at a single tertiary center. The primary outcome of interest was severe disease defined as those requiring intensive care unit (ICU) admission.
Results: The study included 158 consecutive patients. The mean age was 57 years, and 61% were women. The mean (SD) of BMI was 33.2 (8.6) kg/m[SUP]2[/SUP] . Overall, patients admitted to the ICU were older (62 vs. 55 years, P = 0.003) and had higher BMI (36.5 kg/m[SUP]2[/SUP] vs. 31.9 kg/m[SUP]2[/SUP] , P = 0.002). In unadjusted and adjusted analysis, the factors most associated with ICU admission in this sample were age (adjusted odds ratio [aOR]: 1.073; 95% CI: 1.033-1.114), BMI (aOR: 1.115; 95% CI: 1.052-1.182), and lung disease (aOR: 3.097; 95% CI: 1.137-8.437).
Conclusions: This study identified risk factors for severe disease in COVID-19, specifically in an African American population. Further inclusive research aimed at optimizing clinical care relevant to the African American population is critical to ensure an equitable response to COVID-19.