tetano
Editor, Senior Moderator
NPJ Vaccines
. 2020 May 28;5:43.
doi: 10.1038/s41541-020-0198-1. eCollection 2020.
Universal Coronavirus Vaccines: The Time to Start Is Now
Luca T Giurgea[SUP] 1 [/SUP], Alison Han[SUP] 1 [/SUP], Matthew J Memoli[SUP] 1 [/SUP]
Affiliations
Abstract
The continued explosive spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) despite aggressive public health measures has triggered an unprecedented international vaccine effort. However, correlates of protection, which can help guide intelligent vaccine design, are not known for SARS-CoV-2. Research on influenza immunity and vaccine development may provide valuable lessons for coronavirus efforts, especially considering similarities in rapid evolutionary potential. The apparent inevitability of future novel coronavirus outbreaks must prompt work on a universal coronavirus vaccine.
Keywords: Influenza virus; SARS-CoV-2; Vaccines; Viral infection.
. 2020 May 28;5:43.
doi: 10.1038/s41541-020-0198-1. eCollection 2020.
Universal Coronavirus Vaccines: The Time to Start Is Now
Luca T Giurgea[SUP] 1 [/SUP], Alison Han[SUP] 1 [/SUP], Matthew J Memoli[SUP] 1 [/SUP]
Affiliations
- PMID: 32528732
- PMCID: PMC7256035
- DOI: 10.1038/s41541-020-0198-1
Abstract
The continued explosive spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) despite aggressive public health measures has triggered an unprecedented international vaccine effort. However, correlates of protection, which can help guide intelligent vaccine design, are not known for SARS-CoV-2. Research on influenza immunity and vaccine development may provide valuable lessons for coronavirus efforts, especially considering similarities in rapid evolutionary potential. The apparent inevitability of future novel coronavirus outbreaks must prompt work on a universal coronavirus vaccine.
Keywords: Influenza virus; SARS-CoV-2; Vaccines; Viral infection.