Novel reassortants of clade 2.3.4.4 H5N6 highly pathogenic avian influenza viruses possessing genetic heterogeneity in Republic of Korea in late 2017

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J Vet Sci. 2018 Aug 30. [Epub ahead of print]
[h=1]Novel reassortants of clade 2.3.4.4 H5N6 highly pathogenic avian influenza viruses possessing genetic heterogeneity in Republic of Korea in late 2017.[/h] Lee YN[SUP]1[/SUP], Cheon SH[SUP]1[/SUP], Kye SJ[SUP]1[/SUP], Lee EK[SUP]1[/SUP], Sagong M[SUP]1[/SUP], Heo GB[SUP]1[/SUP], Kang YM[SUP]1[/SUP], Cho HK[SUP]1[/SUP], Kim YJ[SUP]1[/SUP], Kang HM[SUP]1[/SUP], Lee MH[SUP]1[/SUP], Lee YJ[SUP]1[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] Novel H5N6 highly pathogenic avian influenza viruses (HPAIVs) were isolated from duck farms and migratory bird habitats in South Korea in November-December 2017. Genetic analysis demonstrated that at least two genotypes of H5N6 were generated through reassortment between clade 2.3.4.4 H5N8 HPAIVs and Eurasian low pathogenic avian influenza virus in migratory birds in late 2017, suggesting frequent reassortment of clade 2.3.4.4 H5 HPAIVs, and highlighting the need for systematic surveillance in Eurasian breeding grounds.


[h=4]KEYWORDS:[/h] H5N6; H5N8; clade 2.3.4.4; highly pathogenic avian influenza; reassortment

PMID: 30173498