tetano
Editor, Senior Moderator
Hepatobiliary Pancreat Dis Int. 2010 Dec;9(6):658-660.
Novel H1N1 influenza A virus infection in a patient with acute rejection after liver transplantation.
He JJ, Yan S, Zhang M, Wang WL, Zheng SS.
Division of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China. shusenzheng@zju.edu.cn.
Abstract
BACKGROUND: The 2009 H1N1 influenza A virus was first identified in April 2009 and rapidly evolved into a pandemic. Recipients of solid-organ transplants have a higher risk for severe infection because of immunosuppression. There are limited reports of 2009 H1N1 influenza in liver transplant recipients, especially in China.
METHODS: We present a case of a 48-year-old male liver transplant recipient with 2009 H1N1 influenza A virus. He received therapy for acute rejection after transplantation and was confirmed with H1N1 virus infection.
RESULTS: The patient was started on oseltamivir (75 mg, orally twice daily) and had a benign hospital course, with defervescence and resolution of symptoms within 72 hours. The follow-up chest radiograph after discharge was normal.
CONCLUSIONS: The 2009 H1N1 influenza in this hospitalized transplant recipient was relatively mild, and prolonged viral shedding was not noted. Oseltamivir can be a valid measure in immunocompromised individuals.
PMID: 21134839 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21134839
Novel H1N1 influenza A virus infection in a patient with acute rejection after liver transplantation.
He JJ, Yan S, Zhang M, Wang WL, Zheng SS.
Division of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China. shusenzheng@zju.edu.cn.
Abstract
BACKGROUND: The 2009 H1N1 influenza A virus was first identified in April 2009 and rapidly evolved into a pandemic. Recipients of solid-organ transplants have a higher risk for severe infection because of immunosuppression. There are limited reports of 2009 H1N1 influenza in liver transplant recipients, especially in China.
METHODS: We present a case of a 48-year-old male liver transplant recipient with 2009 H1N1 influenza A virus. He received therapy for acute rejection after transplantation and was confirmed with H1N1 virus infection.
RESULTS: The patient was started on oseltamivir (75 mg, orally twice daily) and had a benign hospital course, with defervescence and resolution of symptoms within 72 hours. The follow-up chest radiograph after discharge was normal.
CONCLUSIONS: The 2009 H1N1 influenza in this hospitalized transplant recipient was relatively mild, and prolonged viral shedding was not noted. Oseltamivir can be a valid measure in immunocompromised individuals.
PMID: 21134839 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21134839