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Notes from the Field: Nosocomial Outbreak of Middle East Respiratory Syndrome in a Large Tertiary Care Hospital ? Riyadh, Saudi Arabia, 2015

Shiloh

Editor, Senior Moderator
Source: http://www.cdc.gov/mmwr/volumes/65/wr/mm6506a5.htm?s_cid=mm6506a5_e

Notes from the Field: Nosocomial Outbreak of Middle East Respiratory Syndrome in a Large Tertiary Care Hospital ? Riyadh, Saudi Arabia, 2015
Weekly / February 19, 2016 / 65(6);163?164

Hanan H. Balkhy, MD1; Thamer H. Alenazi, MD1; Majid M. Alshamrani, MD1; Henry Baffoe-Bonnie, MD1; Hail M. Al-Abdely, MD3; Aiman El-Saed, MD, PhD1; Hussain A. Al Arbash, MD4; Zayid K. Al Mayahi, MD4; Abdullah M. Assiri, MD5; Abdulaziz bin Saeed, MD5 (View author affiliations)
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Since the first diagnosis of Middle East respiratory syndrome (MERS) caused by the MERS coronavirus (MERS-CoV) in the Kingdom of Saudi Arabia in 2012, sporadic cases and clusters have occurred throughout the country (1). During June?August, 2015, a large MERS outbreak occurred at King Abulaziz Medical City, a 1,200-bed tertiary-care hospital that includes a 150-bed emergency department that registers 250,000 visits per year.

In late June 2015, approximately 3 months after the last previously recognized MERS case in the hospital, a man aged 67 years with multiple comorbidities (diabetes, hypertension, congestive heart failure, and a history of coronary artery bypass graft surgery) and a 10-day history of fever and cough was evaluated in the emergency department (Figure). The patient had no identified exposure to camels. A nasopharyngeal swab from the patient tested positive for MERS-CoV by reverse transcription-polymerase chain reaction (RT-PCR) (2). The patient was admitted and died in the hospital after 31 days. Although this patient?s hospitalization overlapped with the onset of subsequent hospital-associated MERS cases, no direct links between this first case and any of the subsequent cases were identified...
 
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