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Notes From the Field: First Evidence of Locally Acquired Dengue Virus Infection — Maricopa County, Arizona, November 2022

Mary Wilson

Well-known member
March 17, 2023

http://dx.doi.org/10.15585/mmwr.mm7211a5

Melissa Kretschmer, MA[SUP]1[/SUP]; Jennifer Collins, MPH[SUP]1[/SUP]; Ariella P. Dale, PhD[SUP]1[/SUP]; Brenna Garrett[SUP]1[/SUP]; Lia Koski, MPH[SUP]1[/SUP]; Karen Zabel, MSN[SUP]1[/SUP]; R. Nicholas Staab, MD[SUP]1[/SUP]; Katie Turnbow[SUP]1[/SUP]; Judah Nativio, MS[SUP]1[/SUP]; Kelsey Andrews[SUP]1[/SUP]; William E. Smith, MS[SUP]1[/SUP]; John Townsend[SUP]2[/SUP]; Nicole Busser[SUP]2[/SUP]; James Will[SUP]2[/SUP]; Kathryn Burr, DVM[SUP]1[/SUP][SUP],3[/SUP][SUP],4[/SUP]; Forrest K. Jones, PhD[SUP]4[/SUP][SUP],5[/SUP]; Gilberto A. Santiago, PhD[SUP]5[/SUP]; Kelly A. Fitzpatrick, MSPH[SUP]5[/SUP]; Irene Ruberto, PhD[SUP]3[/SUP]; Kathryn Fitzpatrick, MPH[SUP]3[/SUP]; Jessica R. White, DrPH[SUP]1[/SUP]; Laura Adams, DVM[SUP]5[/SUP]; Rebecca H. Sunenshine, MD[SUP]1[/SUP][SUP],6[/SUP]

On November 7, 2022, dengue virus (DENV), which is not endemic in the continental United States (1), was identified in a Maricopa County, Arizona resident by reverse transcription–polymerase chain reaction (RT-PCR) testing at Arizona State Public Health Laboratory (ASPHL). The patient (patient A) was admitted to a hospital on October 19 for a dengue-like illness, 7 days after traveling to and remaining in Mexicali, Mexico for <4 hours. Patient A was hospitalized for 3 days and subsequently recovered. Maricopa County Environmental Services Department (MCESD) conducted retrospective testing for DENV in samples collected from 21 mosquito pools located within 5 miles (8 km) of patient A’s residence during October 1–November 3. A sample collected from one mosquito pool (pool A) on October 5 was positive for DENV. Whole genome sequencing by CDC’s Dengue Branch later revealed that closely related DENV-3 strains not known to be circulating in the patient’s travel region were identified in both patient A and pool A, suggesting local DENV transmission. ...

https://www.cdc.gov/mmwr/volumes/72/wr/mm7211a5.htm
 
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