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Non-influenza viruses in acute respiratory infections among young children. High prevalence of HMPV during the H1N1V.2009 pandemic in Poland

tetano

Editor, Senior Moderator
Przegl Epidemiol. 2014;68(4):627-32.
[h=1]Non-influenza viruses in acute respiratory infections among young children. High prevalence of HMPV during the H1N1V.2009 pandemic in Poland.[/h] [Article in English, Polish]
Pancer KW[SUP]1[/SUP], Gut W[SUP]1[/SUP], Abramczuk E[SUP]1[/SUP], Lipka B[SUP]2[/SUP], Litwińska B[SUP]1[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] In Poland the majority of hospitalized cases of pneumonia (annually more than 70000) were reported without determination of an aetiological agent (J18 of ICD-10), also because diagnosis of viral ARTI is limited to identification of influenza viruses or sometimes RSV.
[h=4]MATERIAL AND METHODS:[/h] For determination the contribution of non-influenza viruses in ARTI among children, 381 nasopharyngeal swabs from hospitalized in period X.2008-IV.2011y. children (aged 1 day - 5 y.o.) were tested for RSV, HMPV, HEV/HRV, HPIV 1-3, HAdV, HBoV.
[h=4]RESULTS:[/h] At least one viral agent was detected in 72.7% of patients. The most predominant was RSV infection (49%), followed by HEV/HRV (15.5%); HMPV (8.7%), Adenoviruses (7.4%), HPIVt.1-3 (5.8%) and HBoV (5.5%). Seven periods based on the median of examined children/month were determined: 3 with increased number of ARTI. RSV infections, diagnosed in all periods, were predominate in five periods, mainly in LRTI cases. In the 3th period - HMPV was predominant, in the 5th - HEV/HRV. It was found that clinical manifestation of HMPV infections varied depending on the period.
[h=4]CONCLUSIONS:[/h] Relatively high prevalence of HBoV or HMPV cases of ARTI, especially different clinical picture in some periods (ARTI without pneumonia or bronchiolitis), indicated necessary of more detailed mo- lecular and epidemiological studies. Also our results indicate the need for improved diagnostic capabilities of virological tests in acute upper and lower respiratory tract infections in children.
[h=4]KEY WORDS:[/h] acute viral respiratory tract infection in young children; seasonality; activity of RSV and HMPV and HBoV.


PMID: 25848781 [PubMed - in process] Free full text
 
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