tetano
Editor, Senior Moderator
Transfusion. 2011 Mar 17. doi: 10.1111/j.1537-2995.2011.03109.x. [Epub ahead of print]
No viremia of pandemic (H1N1) 2009 was demonstrated in blood donors who had donated blood during the probable incubation period.
Sobata R, Matsumoto C, Igarashi M, Uchida S, Momose S, Hino S, Satake M, Tadokoro K.
From the Central Blood Institute, Blood Service Headquarters, Japanese Red Cross Society, Tokyo, Japan.
Abstract
BACKGROUND: In the spring of 2009, the novel swine-origin influenza A (pandemic [H1N1] 2009) virus emerged and spread globally. Although no established cases of transfusion-transmitted influenza have been reported, the widespread outbreak of pandemic (H1N1) 2009 caused serious concern regarding the safety of blood products. The Japanese Red Cross Blood Centers have intercepted blood products with accompanying postdonation information indicating possible pandemic (H1N1) 2009 infection. To study the risk of transmission of pandemic (H1N1) 2009 by blood transfusion, we searched for the viral genome in such products using nucleic acid amplification technology.
STUDY DESIGN AND METHODS: Between June and December 2009, blood components were collected from 579 blood donors who were diagnosed as or strongly suspected of having pandemic (H1N1) 2009 within 7 days after donation. Viral RNA was extracted from plasma and red blood cell (RBC) products, and RNA samples were subjected to real-time reverse transcription-polymerase chain reaction of the hemagglutinin and matrix genes of the pandemic (H1N1) 2009 virus.
RESULTS: A total of 565 plasma and 413 RBC products from the 579 blood donors were available. No viral RNA of the pandemic (H1N1) 2009 was detected in any of the blood samples from the 579 blood donors.
CONCLUSION: No viremia of pandemic (H1N1) 2009 was demonstrated in any of the 579 blood donors who had most likely donated blood during the incubation period. It is considered that the risk of transmitting pandemic (H1N1) 2009 by blood transfusion is extremely low.
? 2011 American Association of Blood Banks.
PMID: 21414008 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21414008
No viremia of pandemic (H1N1) 2009 was demonstrated in blood donors who had donated blood during the probable incubation period.
Sobata R, Matsumoto C, Igarashi M, Uchida S, Momose S, Hino S, Satake M, Tadokoro K.
From the Central Blood Institute, Blood Service Headquarters, Japanese Red Cross Society, Tokyo, Japan.
Abstract
BACKGROUND: In the spring of 2009, the novel swine-origin influenza A (pandemic [H1N1] 2009) virus emerged and spread globally. Although no established cases of transfusion-transmitted influenza have been reported, the widespread outbreak of pandemic (H1N1) 2009 caused serious concern regarding the safety of blood products. The Japanese Red Cross Blood Centers have intercepted blood products with accompanying postdonation information indicating possible pandemic (H1N1) 2009 infection. To study the risk of transmission of pandemic (H1N1) 2009 by blood transfusion, we searched for the viral genome in such products using nucleic acid amplification technology.
STUDY DESIGN AND METHODS: Between June and December 2009, blood components were collected from 579 blood donors who were diagnosed as or strongly suspected of having pandemic (H1N1) 2009 within 7 days after donation. Viral RNA was extracted from plasma and red blood cell (RBC) products, and RNA samples were subjected to real-time reverse transcription-polymerase chain reaction of the hemagglutinin and matrix genes of the pandemic (H1N1) 2009 virus.
RESULTS: A total of 565 plasma and 413 RBC products from the 579 blood donors were available. No viral RNA of the pandemic (H1N1) 2009 was detected in any of the blood samples from the 579 blood donors.
CONCLUSION: No viremia of pandemic (H1N1) 2009 was demonstrated in any of the 579 blood donors who had most likely donated blood during the incubation period. It is considered that the risk of transmitting pandemic (H1N1) 2009 by blood transfusion is extremely low.
? 2011 American Association of Blood Banks.
PMID: 21414008 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21414008