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Nigeria: Polio cases 2009

Shiloh

Editor, Senior Moderator
Source: http://www.ngrguardiannews.com/news...spread drops by 80 per cent in 2009, says WHO

Polio spread drops by 80 per cent in 2009, says WHO

By Chukwuma Muanya

THE number of children in the high risk states in Nigeria who have been paralysed by the wild polio virus in 2009 has declined by over 80 per cent as compared to the same period in 2008, according to the World Health Organisation's (WHO) Country Representative in Nigeria, Dr. Peter Eriki.

Also, the second round of the regional synchronised immunisation campaign involving Nigeria, Benin, Niger, Togo, Ghana, Mali, Burkina Faso and Cote d'Ivoire, kicked off on March 28, 2009.


The exercise, which will end tomorrow, according to officials, is to consolidate on the first synchronised round held from February 28 to March 3, 2009 during which government officials, partners and stakeholders from various countries rallied to ensure the vaccination of eligible children at the border and other areas.

At the presidential kick-off of the March 2009 Immunisation Plus Days (IPDs) Campaign at the Maitama Hospital in Abuja, Eriki described the feat as very significant. He said the WPV1 caused more paralysis than other forms of wild poliovirus and spread more rapidly.

"There is early evidence of improving quality of coverage of immunisation campaigns particularly in the highest risk states. The proportion of un-immunised and under- immunised children in some of the highest risk states is declining," he said.

Eriki, however, sounded a note of caution about the renewed immunisation efforts in the country: "Although the evidence so far is promising, the renewed efforts to improve immunisation coverage needs to be further intensified and sustained, if the goal of stopping transmission is to be achieved."


He suggested that every effort should be made to ensure that the renewed political commitment was translated into improved quality of immunisation, particularly at the community and settlement level where the interaction between parents and service providers takes place. Eriki spoke on behalf of development partners working in the area of health in Nigeria.

The immunisation was kicked off by Vice President Goodluck Jonathan. Others present were Health Ministers, Prof. Babatunde Osotimehin and Dr. Aliyu Idi Hong and the Federal Capital Territory Minister, Senator Adamu Aliero.

Eriki commended the strong commitment of the Nigerian government, especially with the new leadership at the Federal Ministry of Health and the National Primary Healthcare Development Agency.

He reaffirmed the full commitment of the development partners to stand by the government and people of Nigeria in the area of eradicating polio, which he aptly described as 'historic.'

Minister of Health, Prof. Babatunde Osotimehin, assured all concerned that the government and people of Nigeria were determined more than ever before, to make sacrifices to rid the society of the paralysing effects of poliomyelitis and other childhood killer diseases. He said the gains made in the 2008 Integrated Measles Campaign and the efforts to contain the recent outbreaks of Cerebro Spinal Meningitis (CSM) and Lassa fever were testimonies to the Federal Government's resolve.

In 2008, the WHO reported a nine-fold increase in new cases of wild poliovirus type 1 (WPV1) compared with the same period in 2007. This outbreak in northern Nigeria caused major international outbreaks, as occurred in 2003-2006. Also, Nigeria, last year, accounted for 86 per cent of WPV1 cases in the world.
 
Re: Nigeria: Polio cases 2009

Source: http://www.ngrguardiannews.com/focu...t, a concert of efforts against polio, others

Monday, March 30, 2009

On the West Coast, a concert of efforts against polio, others
As Nigeria at the weekend joined other West Africa countries for the second round of the regional synchronized immunization campaign against polio, recent figures from the World Health Organisation (WHO) indicates that the number of children in the high risk states in Nigeria who has been paralyzed by the wild polio virus in 2009 has declined by over 80 per cent as compared to the same period in 2008.

By Chukwuma Muanya and Collins Olayinka

The second round of the regional synchronized polio immunization campaign involving Nigeria, Benin, Niger, Togo, Ghana, Mali, Burkina Faso and Cote d'Ivoire, which kicked off on Saturday March 28, 2009, has re-emphasised the renewed efforts by stakeholders to eradicate the disease.

The exercise which ends on Tuesday March 31, 2009, according to the Count Down to polio eradication in Nigeria, is to consolidate on the first synchronized round held from February 28 to March 3, 2009 during which government officials, partners and stakeholders from various countries rallied to ensure the vaccination of eligible children in the border and other areas.

The Count Down on polio eradication in Nigeria is a monthly online publication by stakeholders.

Also, latest statistics from the World Health Organization (WHO) indicated that the number of children in the high risk states in Nigeria who has been paralyzed by the wild polio virus in 2009 has declined by over 80 per cent as compared to the same period in 2008.

According to Count Down to polio eradication in Nigeria, as at March 20, 2009, 98 children were paralysed by polio in 74 Local Government Areas (LGAs) in 21 states. This is compared to 103 cases in 77 LGAs in 19 states, same period of 2008.

In 2008, the WHO reported a nine-fold increase in new cases of wild poliovirus type 1 (WPV1) compared with the same period in 2007. This outbreak in northern Nigeria caused major international outbreaks, as occurred in 2003-2006. Also, Nigeria, last year, accounted for 86 per cent of WPV1 cases in the world.

There is also a strong drive by the European Union Partnership to Reinforce Immunization Efficiency in Nigeria (EU-PRIME) to use improved routine immunization coverage to fight polio.

Specifically, the project by the European Union was meant to strengthen routine immunization-related activities in the 23 select states with a view to replicating success stories in other states of the federation.


Routine immunization is a programme, which ensures that a child, from birth, gets vaccination against vaccine preventable childhood killer diseases such as polio, tuberculosis, diphtheria, meningitis, whooping cough, measles, chicken pox.

Partners of the Government of in the fight against polio include: United states Centre for disease Control (CDC), Canadian International Development Agency (CIDA), Dangote Ltd, British Department for International Development (DFID), European Union (EU), Gates Foundation, Government of Japan, Korea National Committee, Rotary International, United Nation Children Fund (UNICEF), United States Agency for International Development (USAID,) WHO and World Bank

Medical experts insist that the time has indeed come for a paradigm shift. They say routine immunization holds the key to the early eradication of polio and other vaccine preventable diseases on a sustainable basis in Nigeria.


WHO Country Representative in Nigeria, Dr. Peter Eriki at the occasion of the Presidential flag off of the March 2009 Immunization Plus Days (IPDs) Campaign at the Maitama Hospital in Abuja described the reduction in polio spread as 'very significant.' He said the WPV1 causes more paralysis than other forms of wild polio virus and spreads more rapidly.

"There is early evidence of improving quality of coverage of immunization campaigns particularly in the highest risk states. The proportion of un-immunized and under immunized children in some of the highest risk states is declining," he said.

Eriki, however, sounded a note of caution about the renewed immunization efforts in the country: "Although the evidence so far is promising, the renewed efforts to improve immunization coverage needs to be further intensified and sustained, if the goal of stopping transmission is to be achieved."

He suggested that every effort should be made to ensure that the renewed political commitment is translated into improved quality of immunization particularly at the community and settlement level where the interaction between parents and service providers takes place.

Eriki spoke on behalf of development partners working in the area of health in Nigeria.

The immunization exercise; was flagged off by Vice President, Dr. Jonathan Goodluck. Others present were Health Ministers, Professor Babatunde Osotimehin and Dr. Aliyu Idi Hong and the Federal Capital Territory (FCT) Minister, Senator Adamu Aliero.

Eriki commended the strong commitment of the Nigerian government, especially with the new leadership at the Federal Ministry of Health and the National Primary Healthcare Development Agency.

He reaffirmed the full commitment of the development partners to stand by the Government and people of Nigeria in this initiative to eradicate polio, which he aptly described as 'historic'.

Minister of Health, Professor Babatunde Osotimehin assured all concerned that the government and people of Nigeria are determined more than ever before, to make sacrifices to rid the society of the paralyzing effects of poliomyelitis and other childhood killer diseases. He said the gains made in the 2008 Integrated Measles Campaign and the efforts to contain the recent outbreaks of Cerebro Spinal Meningitis (CSM) and Lassa fever are testimonies of the federal government's resolve.

An immunization Expert and Team Leader of EU-PRIME, Dr Abba Umar said stamping polio out of Nigeria squarely rests on efficient routine immunization at the community level.

"The first step in the six initial states was to build the capacity of the participating states to deliver immunization services within the ambience of the primary healthcare system," he said.

Abba explained: "The EU-PRIME project developed institutional capacity by providing cold chain equipment that is used for vaccine storage to make them potent. 148 vehicles have been procured for distribution to the 23 states to ease movement of vaccines and ensure monitoring and evaluation. Apart from these, the project has also procured 500 motorcycles for distribution to the participating states. With these equipment therefore, it is not surprising that routine immunization coverage has gone up in many folds in these states.

"The realization that the burden of vaccine preventable diseases is more in the rural areas where there is no constant power supply influenced the introduction of solar-powered refrigerators to ensure potency of immunization vaccines."

Abba explained the rationale behind the adoption of the community-based approach. "You and I know that power is not constant in most parts of the country especially in rural communities. The intention is to take solar refrigerators to these areas where there is no electricity or erratic power supply. If the potency of the vaccines should be maintained, there is the need to use a specific system that can work in such an environment and that was the reason we went for solar refrigerators in order to make sure that we administer potent vaccines on the children," he said.


The EU-PRIME boss highlighted that the reason for increasing the number of participating states from the initial six to 23 was informed by the desire to replicate the success story that the project recorded in the initial six states.

To ensure that the routine immunization in the newly added 17 states is shored up, contract for the construction of cold stores was recently awarded in Abuja. The project is being implemented in the following 23 states: Abia, Akwa Ibom, Anambra, Bauchi, Cross River, Ebonyi, Edo, FCT, Gombe, Jigawa, Kaduna , Katsina, Kogi, Kebbi, Kwara, Lagos , Ogun, Osun, Plateau Yobe, Rivers, Sokoto and Zamfara states.


Project Officer for Health, Delegation of the European Commission to Nigeria, Dr. Anthony Ayeke said that the project was midwife to address the burden of vaccine-prevented diseases, which was quite high at the time. In doing this, he said, it was found that there was the need for management coordination of immunization services and coordination of various stakeholders.

His words: "The EU-PRIME has two basic components. The two components were routine immunization and polio eradication. The technical assistance was engaged sometime in 2004 but it did not come on board actively until 2005. So, to adequately quantify what the project has done one has to begin from June 2005 when the technical assistance started. From the indicators that we used such as DPT 3 to measure how well we have done in terms of coverage, reports we got from various states like Kebbi at the inception of the technical assistance, the routine immunization coverage, using DPT 3 as an indicator, was about 1.8 per cent. As at last year when we conducted another study, the coverage was about 82 per cent. In addition to this, we discovered that in states like Kebbi and related states, in 2007 and 2008, the state governments were motivated to buy cold chain equipment on their own which cost almost N1billion. This step is most impressive because it is one of the expected multiplier outcomes of projects like PRIME."

Ayeke said EU-PRIME has helped to provide items such as refrigerators, vaccine carriers and cold chain stores to address the infrastructural gaps and to support the weak routine immunization infrastructure at state and local government levels. Vehicles were also procured for vaccine distribution, monitoring and supervision in the participating states.

Ayeke also said there is no reason to get worried because the project is ending adding that it has achieved the purpose it was set out to achieve.

"There is a financial agreement that cannot be flouted. The project, apart from providing physical structures, has also done very well in awakening the consciousness of key stakeholders on why routine immunization must be strengthened. This awakening is shown in the concerns that have been expressed that the project is ending. The Commissioners of Health in some states have publicly come to say that they will not allow the initiatives spearheaded by the project to die in their states and that they are ready to do whatever it takes to ensure that what the project began is sustained," he explained.

In his assessment of the project, the Executive Director of the National Primary Health Care Development Agency (NPHCDA), Dr Mohammed Pate the agency has recorded resounding success in the effort towards strengthening routine immunization in Nigeria.

He said: "The programme on the whole tried to address a gap in our primary healthcare system by trying to tackling routine immunization. From the report available to me, as a project that has been on in the last couple of years, they have done very well in terms of providing infrastructure, transport logistics, training and capacity building efforts and advocacy in the states that they work."

The NPHCDA boss identified routine immunization as the bedrock upon which polio eradication rests. He also added that if polio would be eradicated from Nigeria, the current approach that has placed supplementary campaign in place of routine immunization must change.

He explained thus: "The supplementary campaign by definition is only supplemental. The polio eradication strategy has four pillars. The first leg is Routine Immunization, which is built around primary health care system to enable that level of care offer routine immunization. The second pillar of the strategy is supposed to be supplemental to routine but what we find in the last couple of years is that the supplemental is becoming the routine while the routine has become supplementary. That is not the way it should be. We are trying to reverse this ugly trend by advocating to state and local governments to invest in routine immunization through additional money, people and materials to ensure availability of routine immunization services while improving the quality and efficiency of the campaigns. The third element is the mop up where there are cases of outbreak and surveillance system. Routine Immunization, in its totality is a proxy for health system performance."


The Kebbi State Commissioner of Health, Alhaji Abubakar Dakin Gari submitted that the renewed efforts have opened a new vista of understanding on why government should commit more resources to strengthen immunization equipment such as cold chain, solar power-refrigerators in the rural areas.

"The project has been a very successful one in Kebbi State . The solar energy provided to power refrigerators in the rural has resulted into ensuring greater efficiency of vaccines. We now have 461 refrigerators spread across the 21 local government areas in the State," he stated.

The Commissioner added that the State is now taking the issue of routine immunization very seriously as it has empowered a technical committee for strengthening routine immunization. Free accommodation has equally been provided to encourage health workers to work in the rural communities.

The Abia State Commissioner of Health, Dr Sam Ahaiwe lauded the project for pushing routine immunization coverage from 21 per cent to 80 per cent in the state. He also said that all the 17 local government areas now have three solar-powered refrigerators each to boost routine immunization at the ward level.

Abba claimed that the impact of the project was also felt in the Niger Delta region where difficult terrain has been identified as a stumbling-block to the immunization drive.

According to Count Down on polio eradication in Nigeria, the quality of the second West Africa synchronized polio campaign at the community level will be the evidence of the commitment of all stakeholders involved.
 
Re: Nigeria: Polio cases 2009

Source: http://www.vanguardngr.com/?p=561

Polio eradication: How Nigeria faced the world at World Health Assembly
Health Jun 9, 2009

By Sola Ogundipe, who was in Geneva
WHEN the 62nd World Health Assembly opened at the Palais de Nations in Geneva Switzerland on May 18, 2009, one of the major health concerns of international interest, besides the (then) looming H1N1 influenza (swine flu) pandemic, was the race towards global target for eradication of poliomyelitis.

Still plagued by the ghosts of the October 2003 controversy surrounding the immunisation programme against polio in which three states in northern Nigeria (Kano, Katsina and Jigawa) boycotted the polio immunisation campaign, it was not surprising that Nigeria has remained squarely in the eye of the storm about polio eradication.

At the time of the boycott, the Global Polio Eradication Initiative had launched what was hoped to be the final onslaught against polio, with a plan to immunise more than 15 million children in West and Central Africa.

There had been particular concerns about the high prevalence of polio cases in Nigeria, and the World Health Organisation (WHO) had it on record that the nation accounted for about 45 per cent of polio cases worldwide and 80 per cent of cases reported from the African region in 2003. The high prevalence was attributed to poor vaccine coverage during the previous control campaigns. No thanks to the boycott, the nation is now one of the four nations (alongside?..) on the yet to interrupt the wild poliovirus transmission.

In 2008, during the 61st WHA, one of the resolutions adopted at the end of the meeting was that Nigeria should strive to ?reduce the risk of international spread of poliovirus.?

Expectedly, this particular resolution was primal on the agenda which the Nigerian delegation to the meeting had committed to address along with issues concerning maternal and child health, malaria control, pandemic influenza prevention and control, non communicable disease prevention and control, and national legislation on health, among others.

So as the 62nd WHA got under way, the world was all ears to know just how far the country had progressed. No one was better placed to tell the story than Nigeria?s own Minister of Health, Prof. Babatunde Osotimehin, who led the 28-man delegation to the event.

Mounting the rostrum, Osotimehin delved into the series of activities and events the nation had undertaken to meet the WHA mandate as far as polio was concerned.

Noting that Nigeria did make appreciable progress in polio eradication from 1998-2002 but suffered a major set-back in 2003-2004 as a result of controversy over the safety of the Oral Polio Vaccine (OPV), he said: ?That setback ensured that Nigeria is one of only four countries yet to interrupt the wild poliovirus transmission in the World. Following this, polio eradication efforts were intensified. These include new innovations aimed at improving effectiveness of polio eradication activities, utilization of the more effective monovalent Oral Polio Vaccine (mOPVs), and mOPV3 with an integrated approach, and adoption of the Immunization Plus Days (IPDs+).

During IPDs, a broad range of child survival interventions resulted in marked improvement of the quality of vaccinations and a significant decline in incidence of wild polio transmission. However progress could not be sustained resulting in a major resurgence of wild polio virus transmission in 2008 such

The Minister elaborated on how the nation placed emphasis on the importance of vaccination is a crucial tool for preventing and controlling the disease.

Already, in line with the resolution adopted at the 61st World Health Assembly urging Nigeria to ?reduce the risk of international spread of poliovirus?, Osotimehin said the nation had quickly stepped up efforts aimed at stopping the polio outbreak in northern Nigeria through intensified eradication activities that ensured vaccination of all children with the oral polio vaccine.

The 62nd WHA was assured that since the 61st WHA one year ago, Nigeria has put in place important measures and have also recorded commendable outcomes. Delegates heared that Nigeria has implemented six rounds of enhanced Supplemental Immunisation Activities (SIAs), three of which have been national campaigns. He said the quality of these campaigns show a steady improvement and the number of Local Government Areas (LGAs) achieving 90 per cent coverage of polio increased to 627 during the March 2009 SIAs. As a result of the steady improvement in quality of the SIAs, the number of unvaccinated children during campaigns declined significantly.

On the revitalising the routine immunisation, the Minister said efforts to improve routine immunisation performance are bearing modest dividends and national routine OPV3 coverage increased from 47 per cent at the beginning of 2008 to 63 per cent in the first quarter in 2009; a 75 per cent increase within 12 months.

Other pointers he gave include Acute Flaccid Paralysis Surveillance. ?In this regard, certification standard (AFP) performance was maintained at national level and in all but one state in 2008. At LGA level, 73 per cent of all LGAs in the country met the two main AFP surveillance performance indicators. Both national polio laboratories in the country located at Ibadan and Maiduguri maintained WHO accreditation in 2008.?

On population immunity, the Minister recalled: ?The improved quality of immunisation activities has impacted positively on population immunity. The proportion of non-polio AFP cases aged 6-35 months reported never to have received a single dose of OPV declined from 15 per cent in 2006 to less than 5 per cent by the first quarter of 2009.

?Similarly, the proportion of non-polio AFP cases aged 6-35 months that were reported to have received at least three dose of OPV increased from 62 per cent in 2006 to 78 per cent by the first quarter of 2009. The most dramatic improvement in population immunity was registered in Kano , where for the first time ever, the children never vaccinated, reduced to less than 20 per cent.?
 
Re: Nigeria: Polio cases 2009

Source: http://en.afrik.com/article15281.html

Polio making a troubling comeback in Nigeria
The Nigerian strain identified as far as Yemen and Indonesia

The world has not seen the last of this disease. Almost eradicated in 2000, polio has returned with a vengeance after the local authorities in the north of Nigeria tragically halted vaccinations ? for over a year, in 2003. The World Health Organization is taking stock.

Friday 26 June 2009, by Will Ghartey-Mould

Twenty years after the Global Polio Eradication Initiative was launched, the number of cases was reduced by no less than 99%. But today, the disease remains endemic in 4 countries: Afghanistan, India, Pakistan and Nigeria.

Nigeria alone accounts for 82% of the total number of cases reported worldwide in 2008.

Without disregarding the impressive inroads that have been done in the area of eradication, the World Health Organisation, nonetheless, points out that as long as a single child continues to be infected, children all over the world will be at risk.

Contrary to the eradication efforts, the polio virus is a long way from being contained.

In recent times, the Nigerian strain of the virus has been identified in non African countries, including Yemen and Indonesia.

As for Africa, the disease is being passed on again in Burkina Faso, Ivory Coast, the Central African Republic, Sudan and Chad. The WHO explains that the cases in the affected African countries are only outbreaks and describes them as manageable.

According to the International health body, the outbreaks have nothing to do with the persistent pockets of polio transmission that are now the focus of their efforts: the north of India, the north of Nigeria and the border area between Afghanistan and Pakistan.

Despite the outbreaks and persistence of the disease in Nigeria the WHO remains confident that the disease will eventually be eradicated.
 
Re: Nigeria: Polio cases 2009

Source: http://www.vanguardngr.com/2009/06/30/delta-confirms-outbreak-of-polio-in-5-lgs/

Delta confirms outbreak of polio in 5 LGs
National News Jun 30, 2009

ASABA?DELTA State Commissioner for Health, Dr. Joseph Otumara, has officially confirmed that there was outbreak of poliomyelitis in five local government areas of the state, just as he called on parents and guardians to bring up their children and wards for what he described as ?another round of supplemental immunization?.

He blamed some local government councils of abysmal failure in effective immunization coverage of their areas.

The commissioner in a broadcast on the recent outbreak of the disease, said he was saddened by the sudden reported seven confirmed cases of wild polio virus in the state and gave the names of the affected local government areas as Ethiope West, Ughelli South, Ughelli North, Bomadi and Patani.

He asked Deltans not ?to overlook the proximity of most of the local governments to each other, as the state has a state of emergency on her hands?.

He has therefore advised parents and guardians ?to bring their children forward without any reservation to benefit from another round of supplemental immunization coming up from July 4 to July 7, 2009?.
 
Re: Nigeria: Polio cases 2009

Polio surge in Nigeria after vaccine virus mutates


Latest News from Nigeria

Polio surge in Nigeria after vaccine virus mutates

LONDON (AP) -- Polio, the dreaded paralyzing disease stamped out in the industrialized world, is spreading in Nigeria. And health officials say in some cases, it's caused by the vaccine used to fight it.

In July, the World Health Organization issued a warning that this vaccine-spread virus might extend beyond Africa. So far, 124 Nigerian children have been paralyzed this year - about twice those afflicted in 2008.

The polio problem is just the latest challenge to global health authorities trying to convince wary citizens that vaccines can save them from dreaded disease. For years, myths have abounded about vaccines - that they were the Western world's plan to sterilize Africans or give them AIDS. The sad polio reality fuels misguided fears and underscores the challenges authorities face using a flawed vaccine.

Nigeria and most other poor nations use an oral polio vaccine because it's cheaper, easier, and protects entire communities.

But it is made from a live polio virus - albeit weakened - which carries a small risk of causing polio for every million or so doses given. In even rarer instances, the virus in the vaccine can mutate into a deadlier version that ignites new outbreaks.

The vaccine used in the United States and other Western nations is given in shots, which use a killed virus that cannot cause polio.

So when WHO officials discovered a polio outbreak in Nigeria was sparked by the polio vaccine itself, they assumed it would be easier to stop than a natural "wild" virus.

They were wrong.

In 2007, health experts reported that amid Nigeria's ongoing outbreak of wild polio viruses, 69 children had also been paralyzed in a new outbreak caused by the mutation of a vaccine's virus.

Back then, WHO said the vaccine-linked outbreak would be swiftly overcome - yet two years later, cases continue to mount. They have since identified polio cases linked to the vaccine dating back as far as 2005.

It is a worrying development for officials who hope to end polio epidemics in India and Africa by the end of this year, after missing several earlier deadlines. "It's very disturbing," said Dr. Bruce Aylward, who heads the polio department at the World Health Organization.

This year, the number of polio cases caused by the vaccine has doubled: 124 children have so far been paralyzed, compared to 62 in 2008, out of about 42 million children vaccinated. For every case of paralysis, there are hundreds of other children who don't develop symptoms, but pass on the disease.

When Nigerian leaders suspended polio vaccination in 2003, believing the vaccine would sterilize their children and infect them with HIV, Nigeria exported polio to nearly two dozen countries worldwide, making it as far away as Indonesia.

Nigeria resumed vaccinations in 2004 after tests showed the vaccine was not contaminated with estrogen, anti-fertility agents or HIV.

Experts have long believed epidemics unleashed by a vaccine's mutated virus wouldn't last since the vaccine only contains a weakened virus strain - but that assumption is coming under pressure. Some experts now say that once viruses from vaccines start circulating they can become just as dangerous as wild viruses.

"The only difference is that this virus was originally in a vaccine vial," said Olen Kew, a virologist at the U.S. Centers for Disease Control and Prevention.

The oral polio vaccine used in Nigeria and elsewhere contains a mild version of the live virus. Children who have been vaccinated pass the virus into the water supply through urine or feces. Other children who then play in or drink that water pick up the vaccine's virus, which gives them some protection against polio.

But in rare instances, as the virus passes through unimmunized children, it can mutate into a strain dangerous enough to ignite new outbreaks, particularly if immunization rates in the rest of the population are low.

Kew said genetic analysis proves mutated viruses from the vaccine have caused at least seven separate outbreaks in Nigeria.

Though Nigeria's coverage rates have improved, up to 15 percent of children in the north still haven't been vaccinated against polio. To eradicate the disease, officials need to reach about 95 percent of the population.

Nigeria's vaccine-linked outbreak underlines the need to stop using the oral polio vaccine as soon as possible, since it can create the very epidemics it was designed to stop, experts say. WHO is researching other vaccines that might work better, but none is on the horizon.

Until a better vaccine is ready, WHO and U.S. CDC officials say the oral vaccine is the best available tool to eradicate polio and that when inoculation rates are nearly 100 percent it works fine.

"Nigeria is almost a case study in what happens when you don't follow the recommendations," Kew said.

Since WHO and partners began their attempt to rid the world of polio in 1988, officials have slashed the disease's incidence by more than 99 percent.

But numerous deadlines have been missed and the number of cases has been at a virtual standstill since 2000. Critics have also wondered whether it is time to give up, and donors may be sick of continuing to fund a program with no clear endgame.

"Eradication is a gamble," said Scott Barrett, an economist at Columbia University who has studied polio policies. "It's all or nothing ... and there is a very real risk this whole thing may fall apart."

Aside from Nigeria, polio persists in a handful of other countries, including Afghanistan, Pakistan, India, Chad, Angola and Sudan.

Aylward agreed the Nigeria situation was another unwelcome hurdle, but was confident eradication was possible. "We still have a shot," he said. "We're throwing everything at it including the kitchen sink."

http://hosted.ap.org/dynamic/storie...RIA?SITE=KFDMTV&SECTION=HOME&TEMPLATE=DEFAULT
 
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