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New York state Global Health Update Report - December 4, 2025

Commonground

Senior Moderator
Date: 12/4/25

This weekly report from the New York State Department of Health presents summaries of select ongoing and emerging

infectious disease outbreaks of interest to public health professionals and the public, both globally and in the United States.

The Global Health Update summaries include preliminary and up-to-date data that are publicly available for these events

at the time of posting. Because this report aggregates and summarizes data and information from outside sources, the

quality, accuracy or completeness of that data, and the appropriateness of the methodology used, cannot be guaranteed.

Please refer directly to those sources for any data questions. Because the report includes preliminary information,

subsequent reports may contain updates or revisions to information in prior reports.

Screenshot 2025-12-08 at 9.20.29 AM.png

Excerpts:
Non-Seasonal Influenza

China – Incident Human Cases Reported from Multiple Provinces (H9N2):

According to data from the Hong Kong Centre for Health Protection (HKCHP), as of December 1, there have been a total

of 14 influenza A(H9N2) cases reported among humans in China during the past 6 months, none of which have been

fatal. On November 18, 2025, 4 incident human H9N2 cases were reported in the Guangxi Zhuang Autonomous Region

(2), Henan Province (1), and Hubei Province (1). Cases reported symptom onset during September (1) and October (3),

were between the ages of 7 months and 12 years, and were exposed to poultry prior to illness onset.

(continued)



United States – Poultry Flock Detections (HPAI); Human Case Update (H5N5):
​-snip-

On November 21, 2025, the Washington State Department of Health reported that the Grays Harbor County resident

that was hospitalized and being treated for H5N5 had died. The individual was an older adult with underlying health

conditions that had been hospitalized since early November. They were exposed to backyard poultry flocks at home that

had exposure to wild birds. There have been 15 human avian influenza cases (12 confirmed and 3 probable) reported in

Washington since October 2024, all of which were exposed to poultry or wild birds prior to illness onset.

According to data from the United States CDC, as of November 24, there have been a total of 71 confirmed influenza

A(H5) cases, including 2 deaths (1, 2), and 7 probable H5 cases reported among humans since the beginning of 2024.

Most were exposed during commercial agriculture and related operations involving dairy cattle and poultry. According to

the CDC, the current risk to public health is low. HPAI continues to be detected among livestock (primarily dairy cattle),

wild birds, and other mammals.

On November 24, 2025, the Pan American Health Organization (PAHO) published an Epidemiological Update regarding

influenza A(H5N1) in the Americas. Since 2022, 19 countries in the Americas have reported a cumulative total of 5,136

H5N1 outbreaks, and 5 countries have reported a cumulative total of 75 human H5N1 cases, including 2 deaths.

Sources: USDA (12/03/25), CDC (11/14/25)

... https://globalhealthreports.health....5-12/Global Health Update 12.4.25 - Final.pdf
 
Date: 12/11/25
​Excerpt:

Non-Seasonal Influenza

United States – Updated Data on Poultry Flock Detections (HPAI):

According to data from the United States Department of Agriculture (USDA), as of December 8, 2025, there have been a

total of 1,936 confirmed highly pathogenic avian influenza (HPAI) detections reported among poultry flocks in the United

States since February 8, 2022. In the past 30 days, a total of 108 confirmed HPAI detections have been reported.
Screenshot 2025-12-13 at 9.21.52 AM.png
Table Notes: Data as of December 8, 2025; The number of detections reported in the past 30 days are based on date of detection/confirmation rather than date of sample collection.


In the past 30 days, HPAI has been detected among poultry flocks in 22 states, primarily Indiana (57). Following a period

with very few detections in June (3), July (1), and August (3), there has been an increase that started in September (29)

and continued through October (67) and November (96). Similar trends have been observed during recent years in the

United States (2022-2024) and globally during 2025.
Screenshot 2025-12-13 at 9.23.28 AM.png

According to data from the United States CDC, as of November 24, there have been a total of 71 confirmed influenza

A(H5) cases, including 2 deaths (1, 2), and 7 probable H5 cases reported among humans since the beginning of 2024. The

most recent human case, and first ever human H5N5 case globally, was reported during November in Washington. Most

were exposed during commercial agriculture and related operations involving dairy cattle and poultry. According to the

CDC, the current risk to public health is low. HPAI continues to be detected among livestock (primarily dairy cattle), wild

birds, and other mammals.

On November 24, 2025, the Pan American Health Organization (PAHO) published an Epidemiological Update regarding

influenza A(H5N1) in the Americas. Since 2022, 19 countries in the Americas have reported a cumulative total of 5,136

H5N1 outbreaks, and 5 countries have reported a cumulative total of 75 human H5N1 cases, including 2 deaths.

Sources: USDA (12/10/25), CDC (11/14/25)

-SNIP-

Seasonal Influenza


Global – Emergence of H3N2 Subclade K as a Predominant Variant:

According to the World Health Organization (WHO), seasonal influenza (flu) activity has been increasing globally since

October, but activity remains within expected seasonal ranges. Variation exists regionally, with some countries in the

northern hemisphere reporting early increases in activity (United Kingdom, North Korea, and Japan), and some counties

in the southern hemisphere reporting longer seasons (Australia & New Zealand), compared to prior years. The Pan

American Health Organization (PAHO) recently issued an Epidemiological Alert regarding the end of flu season in the

southern hemisphere, beginning of flu season in the northern hemisphere, and the recent increase in circulation and

predominance of influenza A(H3N2) subclade K (J.2.4.1) virus in Europe and several countries in Asia. Additionally, PAHO

stressed the importance of closely monitoring the evolution of the virus, ensuring preparedness for this flu season, and

maintaining high vaccination coverage particularly among older adults and those with risk factors.

Globally, Influenza A viruses are the predominant type detected among tested samples; however, since August, there has

been a rapid increase in the proportion of influenza A(H3N2) subclade K (J.2.4.1) detected in many countries based on

genetic sequence data. While this subclade marks a notable evolution (or drift) in influenza A(H3N2) viruses, current

epidemiological data does not indicate greater disease severity. Early estimates suggest that the current seasonal flu

vaccine continues to provide protection against hospitalization among both children and adults, though its effectiveness

against clinical disease during the current season is undetermined.

In the United States, seasonal influenza activity is increasing, with the largest increases reported among children and young

adults and in the northeastern and mountain west areas of the country (HHS regions 1, 2, and 8). The timing of this

increase is like several past seasons. As of November 29, 2025, the United States CDC estimates that there have been at

least 1.9 million illnesses, 19,000 hospitalizations, and 730 deaths from flu so far this season. No influenza-associated

pediatric deaths occurring during the 2025-2026 season have been reported. Influenza A(H3N2) has been detected in

84.3% of positive specimens collected. Genetic characterization of Influenza A(H3N2) positive specimens shows 43.8%

belong to subclade K.

Sources: WHO (12/10/25), ECDC (12/5/25), CDC (12/4/25), PAHO (12/04/25)

... https://globalhealthreports.health....-12/Global Health Update 12.11.25 - Final.pdf

 
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