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New York City: Genome Sequence of Canine Polyomavirus in Respiratory Secretions of Dogs with (fatal) Pneumonia of Unknown Etiology

Emily

Editor, Senior Moderator
This is very sad. I wonder if the puppy was bred in a facility that bred NHP's?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522929/
Delwart E, Kapusinszky B, Pesavento PA, Estrada M, Seguin MA, Leutenegger CM. 2017. Genome sequence of canine polyomavirus in respiratory secretions of dogs with pneumonia of unknown etiology. Genome Announc 5:e00615-17. https://doi.org/10.1128/genomeA.00615-17. ABSTRACT

We report here the first canine polyomavirus genome, identified by metagenomics in respiratory secretions of two dogs with severe pneumonia, which tested negative for all canine respiratory pathogens except Mycoplasma cynos. The isolate, Canis familiaris polyomavirus 1 (DogPyV-1), is a beta polyomavirus whose closest known LT antigen relatives are primate polyomaviruses.

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GENOME ANNOUNCEMENT

Three dogs from the same household in the New York City area developed respiratory symptoms in November 2015 following the introduction of a Labrador retriever puppy from a pet store. The puppy fell ill with respiratory signs shortly after joining the household but recovered uneventfully. Two unrelated 10-year-old Dachshunds in the household became sick shortly afterward. One Dachshund died, while the second was diagnosed with pneumonia based on thoracic radiography showing severe diffuse pulmonary infiltrates. Despite intensive antibiotic therapy, this dog was later euthanized due to progressive disease....
 
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