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http://www.bionity.com/news/e/66307/?WT.mc_id=ca0068
excerts:
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18 Jul 2007 - Scientists from The Scripps Research Institute have developed a breakthrough methodology that can be used to rapidly predict how viruses will mutate in response to attacks by the immune system. The new approach, dubbed "checkmate analysis," may also predict which antibodies or small molecule therapeutics will best neutralize these viral mutations before they can develop into global epidemics.
Because of its simplicity and low cost, this innovative approach will be accessible to scientists around the world.
The new study was published in an advanced online edition of journal Proceedings of the National Academy of Sciences in July 2007.
The new method starts with large libraries of mutant viral proteins and antibodies that are expressed on a phage surface.These two factions are then used to challenge each other.
These proteins are frequently assembled in cell membranes and often composed of various subunits, as is the case with hemagglutinin (HA) ...influenza
excerts:
---------
18 Jul 2007 - Scientists from The Scripps Research Institute have developed a breakthrough methodology that can be used to rapidly predict how viruses will mutate in response to attacks by the immune system. The new approach, dubbed "checkmate analysis," may also predict which antibodies or small molecule therapeutics will best neutralize these viral mutations before they can develop into global epidemics.
Because of its simplicity and low cost, this innovative approach will be accessible to scientists around the world.
The new study was published in an advanced online edition of journal Proceedings of the National Academy of Sciences in July 2007.
The new method starts with large libraries of mutant viral proteins and antibodies that are expressed on a phage surface.These two factions are then used to challenge each other.
These proteins are frequently assembled in cell membranes and often composed of various subunits, as is the case with hemagglutinin (HA) ...influenza