tetano
Editor, Senior Moderator
New Microbes New Infect
. 2020 Oct 5;100777.
doi: 10.1016/j.nmni.2020.100777. Online ahead of print.
Demographics, laboratory parameters and outcomes of 1061 patients with COVID-19: A report from Tehran, Iran
Mihan Pourabdollah Toutkaboni[SUP] 1 [/SUP], Elham Askari[SUP] 1 [/SUP], Nastaran Khalili[SUP] 2 3 [/SUP], Payam Tabarsi[SUP] 4 [/SUP], Hamidreza Jamaati[SUP] 1 [/SUP], Ali Akbar Velayati[SUP] 5 [/SUP], Atosa Dorudinia[SUP] 1 [/SUP], Mitrasadat Rezaei[SUP] 6 [/SUP], Seyed Alireza Nadji[SUP] 6 [/SUP], Abdolreza Mohamadnia[SUP] 1 [/SUP], Neda Khalili[SUP] 2 3 [/SUP]
Affiliations
Abstract
We aimed to determine the characteristics of coronavirus disease-2019 among the Iranian population. In this study, we collected and analyzed the demographics, laboratory findings and outcomes of patients with COVID-19 who were admitted to Masih Daneshvari Hospital in Tehran, Iran between February 20, 2020 and April 2, 2020. Of 1061 patients, the median age was 55 years (interquartile range [IQR], 44-66 years) and 692 (65.2%) were male. Among these, 129 (12.2%) patients died at some point during hospitalization in the ward or intensive care unit (ICU). From the remaining 932 survivors, 46 (5.0%) patients were admitted to the ICU and 886 (95.0%) patients were hospitalized in the ward. Patients who died were significantly older than those hospitalized in the ward (p<0.001). The median absolute number of lymphocytes was 1.2 ? 10[SUP]3[/SUP] per microliter (IQR, 0.9-1.6 ? 10[SUP]3[/SUP] per microliter) and 708 (66.7%) patients had lymphopenia (absolute lymphocyte count <1500 per microliter). Among the laboratory tests, D-dimer, serum ferritin and albumin had the strongest correlation with mortality (r = 0.455, r = 0.412, r = -0.406, respectively; p-values <0.001). Conclusively, laboratory findings could provide useful information in regard to the management of patients with COVID-19.
Keywords: COVID-19; Coronavirus disease 2019; Iran; Laboratory; Lymphocyte.
. 2020 Oct 5;100777.
doi: 10.1016/j.nmni.2020.100777. Online ahead of print.
Demographics, laboratory parameters and outcomes of 1061 patients with COVID-19: A report from Tehran, Iran
Mihan Pourabdollah Toutkaboni[SUP] 1 [/SUP], Elham Askari[SUP] 1 [/SUP], Nastaran Khalili[SUP] 2 3 [/SUP], Payam Tabarsi[SUP] 4 [/SUP], Hamidreza Jamaati[SUP] 1 [/SUP], Ali Akbar Velayati[SUP] 5 [/SUP], Atosa Dorudinia[SUP] 1 [/SUP], Mitrasadat Rezaei[SUP] 6 [/SUP], Seyed Alireza Nadji[SUP] 6 [/SUP], Abdolreza Mohamadnia[SUP] 1 [/SUP], Neda Khalili[SUP] 2 3 [/SUP]
Affiliations
- PMID: 33042553
- PMCID: PMC7534790
- DOI: 10.1016/j.nmni.2020.100777
Abstract
We aimed to determine the characteristics of coronavirus disease-2019 among the Iranian population. In this study, we collected and analyzed the demographics, laboratory findings and outcomes of patients with COVID-19 who were admitted to Masih Daneshvari Hospital in Tehran, Iran between February 20, 2020 and April 2, 2020. Of 1061 patients, the median age was 55 years (interquartile range [IQR], 44-66 years) and 692 (65.2%) were male. Among these, 129 (12.2%) patients died at some point during hospitalization in the ward or intensive care unit (ICU). From the remaining 932 survivors, 46 (5.0%) patients were admitted to the ICU and 886 (95.0%) patients were hospitalized in the ward. Patients who died were significantly older than those hospitalized in the ward (p<0.001). The median absolute number of lymphocytes was 1.2 ? 10[SUP]3[/SUP] per microliter (IQR, 0.9-1.6 ? 10[SUP]3[/SUP] per microliter) and 708 (66.7%) patients had lymphopenia (absolute lymphocyte count <1500 per microliter). Among the laboratory tests, D-dimer, serum ferritin and albumin had the strongest correlation with mortality (r = 0.455, r = 0.412, r = -0.406, respectively; p-values <0.001). Conclusively, laboratory findings could provide useful information in regard to the management of patients with COVID-19.
Keywords: COVID-19; Coronavirus disease 2019; Iran; Laboratory; Lymphocyte.