tetano
Editor, Senior Moderator
Neurologist
. 2021 May 5;26(3):86-89.
doi: 10.1097/NRL.0000000000000311.
Concurrent Stroke and Myocardial Infarction After Mild COVID-19 Infection
Gerardo Ruiz-Ares[SUP] 1 [/SUP], Santiago Jimenez-Valero[SUP] 2 [/SUP], Andr?s Fern?ndez-Prieto[SUP] 3 [/SUP], Emilio Arbas-Redondo[SUP] 2 [/SUP], Beatriz D?az-Poll?n[SUP] 4 [/SUP], Pedro Navia[SUP] 3 [/SUP], Pablo Meras[SUP] 2 [/SUP], Maria Alonso de Leci?ana[SUP] 1 [/SUP], Jorge R P de Doneb?n[SUP] 1 [/SUP], Ricardo Rigual[SUP] 1 [/SUP], Blanca Fuentes[SUP] 1 [/SUP], Exuperio D?ez-Tejedor[SUP] 1 [/SUP]
Affiliations
Abstract
Introduction: The concurrency of both, acute stroke and acute myocardial infarction in normal conditions, outside the pandemic is rare. Coagulopathy has been associated with the inflammatory phase of coronavirus disease (COVID-19) and might be involved in this concurrency.
Cases report: We describe 2 patients with previous mild or no symptoms of COVID-19, admitted for acute stroke with recent/simultaneous myocardial infarction in whom admission polymerase chain reaction was negative but serologic testing diagnosed COVID-19. In these patients, concurrent stroke and myocardial infarction could have been promoted by COVID-19 infection. Management and evolution are detailed, and their contacts to confirm the COVID-19 infection. Pathogenic analysis of possible hypercoagulation state is described suggesting the hypothesis of endothelial dysfunction as the strongest mechanism involved in thrombus formation after the acute phase of COVID-19 infection.
Conclusions: Our experience with these cases suggests that patients with mild symptoms can also present thromboembolic complications once the acute phase of COVID-19 infection has passed.
. 2021 May 5;26(3):86-89.
doi: 10.1097/NRL.0000000000000311.
Concurrent Stroke and Myocardial Infarction After Mild COVID-19 Infection
Gerardo Ruiz-Ares[SUP] 1 [/SUP], Santiago Jimenez-Valero[SUP] 2 [/SUP], Andr?s Fern?ndez-Prieto[SUP] 3 [/SUP], Emilio Arbas-Redondo[SUP] 2 [/SUP], Beatriz D?az-Poll?n[SUP] 4 [/SUP], Pedro Navia[SUP] 3 [/SUP], Pablo Meras[SUP] 2 [/SUP], Maria Alonso de Leci?ana[SUP] 1 [/SUP], Jorge R P de Doneb?n[SUP] 1 [/SUP], Ricardo Rigual[SUP] 1 [/SUP], Blanca Fuentes[SUP] 1 [/SUP], Exuperio D?ez-Tejedor[SUP] 1 [/SUP]
Affiliations
- PMID: 33942789
- DOI: 10.1097/NRL.0000000000000311
Abstract
Introduction: The concurrency of both, acute stroke and acute myocardial infarction in normal conditions, outside the pandemic is rare. Coagulopathy has been associated with the inflammatory phase of coronavirus disease (COVID-19) and might be involved in this concurrency.
Cases report: We describe 2 patients with previous mild or no symptoms of COVID-19, admitted for acute stroke with recent/simultaneous myocardial infarction in whom admission polymerase chain reaction was negative but serologic testing diagnosed COVID-19. In these patients, concurrent stroke and myocardial infarction could have been promoted by COVID-19 infection. Management and evolution are detailed, and their contacts to confirm the COVID-19 infection. Pathogenic analysis of possible hypercoagulation state is described suggesting the hypothesis of endothelial dysfunction as the strongest mechanism involved in thrombus formation after the acute phase of COVID-19 infection.
Conclusions: Our experience with these cases suggests that patients with mild symptoms can also present thromboembolic complications once the acute phase of COVID-19 infection has passed.