tetano
Editor, Senior Moderator
Neurol Sci
. 2022 Sep 2.
doi: 10.1007/s10072-022-06373-5. Online ahead of print.
Limited evidence for neuropsychological dysfunction in patients initially affected by severe COVID-19
Konstantinos Priftis[SUP] 1 2 [/SUP], Valeria Velardo[SUP] 3 [/SUP], Matteo Giuseppe Felice Vascello[SUP] 3 [/SUP], Stella Villella[SUP] 3 [/SUP], Silvia Galeri[SUP] 3 [/SUP], Maria Simonetta Spada[SUP] 4 [/SUP], Lorella Algeri[SUP] 3 [/SUP]
Affiliations
Abstract
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), resulting in coronavirus disease 2019 (COVID-19), has caused a pandemic. There is now considerable evidence that neuropsychological functions could be affected. We further tested this hypothesis on a sample of post COVID-19 patients, who, initially, had been severely affected.
Methods: We tested 22 post COVID-19 patients who, after the intensive care unit (all but one), were admitted to our rehabilitation unit to be treated for severe post COVID-19 sequelae. All patients were administered a comprehensive neuropsychological battery including measures assessing perceptual, attentive, mnestic, linguistic, and executive functions, and overall cognitive status. The patients were also administered rehabilitation measures including scales for investigating aerobic capacity/endurance deficits, dyspnea, and fatigue.
Results: Our findings revealed that evidence of neuropsychological disorders in post COVID-19 patients was very limited. Furthermore, COVID-19 severity and other relevant variables were not correlated with patients' scores on the neuropsychological tests.
Conclusions: We suggest that the relation between COVID-19 and neuropsychological disorders is unclear. New studies and metanalyses are highly required to shed light on this highly complex issue.
Keywords: COVID-19; Neuropsychological assessment; Neuropsychology; SARS-CoV-2.
. 2022 Sep 2.
doi: 10.1007/s10072-022-06373-5. Online ahead of print.
Limited evidence for neuropsychological dysfunction in patients initially affected by severe COVID-19
Konstantinos Priftis[SUP] 1 2 [/SUP], Valeria Velardo[SUP] 3 [/SUP], Matteo Giuseppe Felice Vascello[SUP] 3 [/SUP], Stella Villella[SUP] 3 [/SUP], Silvia Galeri[SUP] 3 [/SUP], Maria Simonetta Spada[SUP] 4 [/SUP], Lorella Algeri[SUP] 3 [/SUP]
Affiliations
- PMID: 36050424
- DOI: 10.1007/s10072-022-06373-5
Abstract
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), resulting in coronavirus disease 2019 (COVID-19), has caused a pandemic. There is now considerable evidence that neuropsychological functions could be affected. We further tested this hypothesis on a sample of post COVID-19 patients, who, initially, had been severely affected.
Methods: We tested 22 post COVID-19 patients who, after the intensive care unit (all but one), were admitted to our rehabilitation unit to be treated for severe post COVID-19 sequelae. All patients were administered a comprehensive neuropsychological battery including measures assessing perceptual, attentive, mnestic, linguistic, and executive functions, and overall cognitive status. The patients were also administered rehabilitation measures including scales for investigating aerobic capacity/endurance deficits, dyspnea, and fatigue.
Results: Our findings revealed that evidence of neuropsychological disorders in post COVID-19 patients was very limited. Furthermore, COVID-19 severity and other relevant variables were not correlated with patients' scores on the neuropsychological tests.
Conclusions: We suggest that the relation between COVID-19 and neuropsychological disorders is unclear. New studies and metanalyses are highly required to shed light on this highly complex issue.
Keywords: COVID-19; Neuropsychological assessment; Neuropsychology; SARS-CoV-2.