tetano
Editor, Senior Moderator
Neurol Res Int
. 2020 Nov 4;2020:7397480.
doi: 10.1155/2020/7397480. eCollection 2020.
Acute Ischemic Stroke in COVID-19: Putative Mechanisms, Clinical Characteristics, and Management
Ademola S Ojo[SUP] 1 [/SUP], Simon A Balogun[SUP] 2 [/SUP], Ahmed O Idowu[SUP] 3 [/SUP]
Affiliations
Abstract
The emergence and spread of the highly contagious novel coronavirus disease (COVID-19) have triggered the greatest public health challenge of the last century. Aside from being a primary respiratory disease, acute ischemic stroke has emerged as a complication of the disease. While current evidence shows COVID-19 could cause ischemic stroke especially in severe disease, there are similarities in the risk factors for severe COVID-19 as well as ischemic stroke, underscoring the complex relationship between these two conditions. The pandemic has created challenges for acute stroke care. Rapid assessment and time-sensitive interventions required for optimum outcomes in acute stroke care have been complicated by COVID-19 due to the need for disease transmission preventive measures. The purpose of this article is to explore the putative mechanisms of ischemic stroke in COVID-19 and the clinical characteristics of COVID-19 patients who develop ischemic stroke. In addition, we discuss the challenges of managing acute ischemic stroke in the setting of COVID-19 and review current management guidelines. We also highlighted potential areas for future research.
. 2020 Nov 4;2020:7397480.
doi: 10.1155/2020/7397480. eCollection 2020.
Acute Ischemic Stroke in COVID-19: Putative Mechanisms, Clinical Characteristics, and Management
Ademola S Ojo[SUP] 1 [/SUP], Simon A Balogun[SUP] 2 [/SUP], Ahmed O Idowu[SUP] 3 [/SUP]
Affiliations
- PMID: 33224529
- PMCID: PMC7673935
- DOI: 10.1155/2020/7397480
Abstract
The emergence and spread of the highly contagious novel coronavirus disease (COVID-19) have triggered the greatest public health challenge of the last century. Aside from being a primary respiratory disease, acute ischemic stroke has emerged as a complication of the disease. While current evidence shows COVID-19 could cause ischemic stroke especially in severe disease, there are similarities in the risk factors for severe COVID-19 as well as ischemic stroke, underscoring the complex relationship between these two conditions. The pandemic has created challenges for acute stroke care. Rapid assessment and time-sensitive interventions required for optimum outcomes in acute stroke care have been complicated by COVID-19 due to the need for disease transmission preventive measures. The purpose of this article is to explore the putative mechanisms of ischemic stroke in COVID-19 and the clinical characteristics of COVID-19 patients who develop ischemic stroke. In addition, we discuss the challenges of managing acute ischemic stroke in the setting of COVID-19 and review current management guidelines. We also highlighted potential areas for future research.