tetano
Editor, Senior Moderator
Neurol Clin Pract
. 2021 Apr;11(2):e147-e151.
doi: 10.1212/CPJ.0000000000000900.
Acute Hemorrhagic Encephalitis Related to COVID-19
Alan Chalil[SUP] 1 [/SUP], Carmen S Baker[SUP] 1 [/SUP], Robert B Johnston[SUP] 1 [/SUP], Caroline Just[SUP] 1 [/SUP], Derek B Debicki[SUP] 1 [/SUP], Michael S Mayich[SUP] 1 [/SUP], Karen J Bosma[SUP] 1 [/SUP], David A Steven[SUP] 1 [/SUP]
Affiliations
Abstract
Purpose of review: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the most critical public health challenge in recent history. In this report, we present a case of suspected acute hemorrhagic encephalitis with bilateral intracranial hemorrhages associated with coronavirus disease 2019 (COVID-19) infection.
Recent findings: A 48-year-old female COVID-19-positive patient developed acute changes in her neurologic status. A head CT with CT angiography demonstrated extensive bilateral parietal and occipital intraparenchymal hemorrhage with intraventricular extension and acute hydrocephalus. The patient was treated with an external ventricular drain, and a CSF sample was tested for SARS-CoV-2 but was found to be negative.
Summary: The underlying mechanism for developing acute hemorrhagic encephalitis in viral illnesses may be autoimmune in nature and warrants further investigation. The initial neurologic presentation of COVID-19-related hemorrhagic encephalitis is altered level of consciousness, which may prompt further neurologic examination and imaging to exclude this feature.
. 2021 Apr;11(2):e147-e151.
doi: 10.1212/CPJ.0000000000000900.
Acute Hemorrhagic Encephalitis Related to COVID-19
Alan Chalil[SUP] 1 [/SUP], Carmen S Baker[SUP] 1 [/SUP], Robert B Johnston[SUP] 1 [/SUP], Caroline Just[SUP] 1 [/SUP], Derek B Debicki[SUP] 1 [/SUP], Michael S Mayich[SUP] 1 [/SUP], Karen J Bosma[SUP] 1 [/SUP], David A Steven[SUP] 1 [/SUP]
Affiliations
- PMID: 33842083
- PMCID: PMC8032421 (available on 2022-04-01)
- DOI: 10.1212/CPJ.0000000000000900
Abstract
Purpose of review: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the most critical public health challenge in recent history. In this report, we present a case of suspected acute hemorrhagic encephalitis with bilateral intracranial hemorrhages associated with coronavirus disease 2019 (COVID-19) infection.
Recent findings: A 48-year-old female COVID-19-positive patient developed acute changes in her neurologic status. A head CT with CT angiography demonstrated extensive bilateral parietal and occipital intraparenchymal hemorrhage with intraventricular extension and acute hydrocephalus. The patient was treated with an external ventricular drain, and a CSF sample was tested for SARS-CoV-2 but was found to be negative.
Summary: The underlying mechanism for developing acute hemorrhagic encephalitis in viral illnesses may be autoimmune in nature and warrants further investigation. The initial neurologic presentation of COVID-19-related hemorrhagic encephalitis is altered level of consciousness, which may prompt further neurologic examination and imaging to exclude this feature.