tetano
Editor, Senior Moderator
Neurodegener Dis Manag
. 2021 Dec 2.
doi: 10.2217/nmt-2021-0025. Online ahead of print.
COVID-19-associated encephalitis or Creutzfeldt-Jakob disease: a case report
Gooya Tayyebi[SUP] 1 [/SUP], Seyed Kazem Malakouti[SUP] 1 [/SUP], Behnam Shariati[SUP] 1 [/SUP], Leila Kamalzadeh[SUP] 1 [/SUP]
Affiliations
Abstract
Background: Accurate diagnosis and management of patients with rapidly progressive dementia may be challenging during the COVID-19 pandemic, which has negatively influenced the diagnostic performances, medical resource allocation and routine care for all non-COVID-19 diseases. Case Presentation: We herein present a case of a 57-year-old male with rapidly progressive cognitive decline, headache, diplopia, myalgia, unsteady gait, aggression, depression, insomnia, hallucinations and delusions of persecution. COVID-19-associated encephalitis was briefly considered as a differential diagnosis. However, this hypothesis was rejected upon further investigation. A final diagnosis of sporadic Creutzfeldt-Jakob disease was made. Conclusion: A timely and accurate diagnosis of Creutzfeldt-Jakob disease gives patients and their families the chance to receive a good standard of healthcare and avoid extensive evaluations for other conditions.
Keywords: COVID-19; Creutzfeldt–Jakob disease; SARS-CoV-2; coronavirus; encephalitis; prion diseases.
. 2021 Dec 2.
doi: 10.2217/nmt-2021-0025. Online ahead of print.
COVID-19-associated encephalitis or Creutzfeldt-Jakob disease: a case report
Gooya Tayyebi[SUP] 1 [/SUP], Seyed Kazem Malakouti[SUP] 1 [/SUP], Behnam Shariati[SUP] 1 [/SUP], Leila Kamalzadeh[SUP] 1 [/SUP]
Affiliations
- PMID: 34854312
- DOI: 10.2217/nmt-2021-0025
Abstract
Background: Accurate diagnosis and management of patients with rapidly progressive dementia may be challenging during the COVID-19 pandemic, which has negatively influenced the diagnostic performances, medical resource allocation and routine care for all non-COVID-19 diseases. Case Presentation: We herein present a case of a 57-year-old male with rapidly progressive cognitive decline, headache, diplopia, myalgia, unsteady gait, aggression, depression, insomnia, hallucinations and delusions of persecution. COVID-19-associated encephalitis was briefly considered as a differential diagnosis. However, this hypothesis was rejected upon further investigation. A final diagnosis of sporadic Creutzfeldt-Jakob disease was made. Conclusion: A timely and accurate diagnosis of Creutzfeldt-Jakob disease gives patients and their families the chance to receive a good standard of healthcare and avoid extensive evaluations for other conditions.
Keywords: COVID-19; Creutzfeldt–Jakob disease; SARS-CoV-2; coronavirus; encephalitis; prion diseases.