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Update 20 October 2025: First reported case of mpox variant 1b in the Netherlands
On 17 October 2025, an mpox infection involving the new mpox variant 1b was diagnosed in the Netherlands. It is the first time that this new mpox variant has been confirmed in the Netherlands.
The patient had not been vaccinated against mpox. He did not have any recent travel history, but had been active among men who have sex with men (MSM).
The patient is in isolation and the local Municipal Public Health Service (GGD) is conducting source and contact tracing. The risk of further transmission seems low.
Local spread of mpox variant 1b was also recently reported in Spain and in the USA. The situation is being monitored closely by the ECDC and WHO.