sharon sanders
Editor-in-Chief & President
[h=1]Zika Virus Associated with Meningoencephalitis[/h] March 9, 2016DOI: 10.1056/NEJMc1602964
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Several electroencephalograms showed no direct signs that were suggestive of epilepsy during levetiracetam therapy (which was administered for the first time in the ICU because seizure had been suspected as one of the mechanisms of the initial consciousness disorder). Spontaneous arousal occurred within 24 hours after intubation, and mechanical ventilation was weaned on day 2. At that time, the patient was awake but had spatial delusion with visual and kinesthetic hallucinations and a persisting weakness (2/5) of the left arm. His neurologic condition continued to improve without specific treatment. He was discharged from the ICU on day 17, and his cognitive function was fully recovered by day 38. He had a residual weakness (4/5) of the left arm. Clinicians should be aware that ZIKV may be associated with meningoencephalitis.
http://www.nejm.org/doi/full/10.1056/NEJMc1602964?query=featured_home
snip
Several electroencephalograms showed no direct signs that were suggestive of epilepsy during levetiracetam therapy (which was administered for the first time in the ICU because seizure had been suspected as one of the mechanisms of the initial consciousness disorder). Spontaneous arousal occurred within 24 hours after intubation, and mechanical ventilation was weaned on day 2. At that time, the patient was awake but had spatial delusion with visual and kinesthetic hallucinations and a persisting weakness (2/5) of the left arm. His neurologic condition continued to improve without specific treatment. He was discharged from the ICU on day 17, and his cognitive function was fully recovered by day 38. He had a residual weakness (4/5) of the left arm. Clinicians should be aware that ZIKV may be associated with meningoencephalitis.
http://www.nejm.org/doi/full/10.1056/NEJMc1602964?query=featured_home